Mydocalm from the back helps. Sirdalud (Sirdalud) or Mydocalm (Mydocalm). What is better, more effective in cervical osteochondrosis, spinal hernia, lumbar disease. Hernia. The concept and reasons for the appearance

Mydocalm is a modern pharmacological agent used to eliminate pain. The drug has an effect on the central nervous system, so it is not recommended to take it without medical supervision. And this is especially true for medicine in ampoules. In some cases, they can cause suffocation, lack of air.

Indications

As a rule, the doctor prescribes Mydocalm if there are indications for use, such as:

• ischemic stroke, vasospasm in the brain;
• encephalopathy;
• central nervous genesis;
• pain syndrome caused, including;
• lower extremities;
• obliterating endarteritis;
• pronounced severe pain syndrome against the background of the development of hemorrhoids;
• menstrual pain;
• the threat of miscarriage due to hypertonicity of the muscular structures of the uterus;
• cholelithiasis.

The drug mydocalm in tablets and injections according to the instructions for use is prescribed during the rehabilitation period after various surgical interventions. It has a positive effect on the level of stretching of muscle fibers.

The scheme of application of the drug

The scheme of use by the doctor is drawn up based on the severity of the symptoms and the patient's tolerance for the drug Mydocalm.

Usually the daily dose of the drug in tablet form for adult patients is 150-450 mg, divided into three doses. Reception begins with a minimum dosage of 50 mg three times a day. If there is no effect, the dose is increased.

When prescribing the drug in the form of intramuscular injections, it is prescribed 200 mg per day (in 2 doses), with intravenous administration, the daily dose is 100 mg (in 1 dose).

With intravenous administration of mydocalm, the doctor uses the drip method, which is considered the most effective. Intramuscular injections also act quickly. The price of the medicine in ampoules is around 300 rubles, but it justifies the money spent.

Small patients, aged 3 months. - 7 years Mydocalm is prescribed based on weight: 5-15 mg / kg (three times a day). Older patients - 7-15 years old - are recommended orally 3-5 mg / kg per day (three times a day). The drug is taken with food.

Side effects and contraindications

If there is a reaction to the components that make up the drug, this manifests itself in the form side effects:

• headache;
• nausea, vomiting;
• muscle weakness.

Allergic manifestations are possible: itching; erythematous rashes; .

With improper jet administration intravenously (this is highly undesirable), arterial hypotension often occurs. If you reduce the dosage, as a rule, signs of side effects disappear or become less pronounced.

Contraindications. In medicine, it has been established that Mydocalm cannot be used if there are contraindications:

• myasthenia gravis;
• if the patient is allergic to the drug (when prescribing an ampouled form) or to;
• children under the age of 3 months.

Solution in ampoules

Mydocalm Richter is a solution intended for the administration of the drug intramuscularly, intravenously. The solution is almost colorless, has a slightly greenish tint and a specific smell. According to the instructions for use, the composition of the drug includes tolperisone hydrochloride and lidocaine hydrochloride. This provides a local anesthetic effect.

Prescribing the drug during pregnancy

To date, there is no evidence that mydocalm is absolutely harmless to pregnant and lactating women. However, he is assigned to medical practice pregnant women (in the first trimester), as well as lactating women, if necessary. At the same time, it is important that positive therapeutic effect, which the patient wishes to receive, did not cause the risk of negative consequences for the fetus or newborn.

Efficiency

Mydocalm has been successfully used in many countries. It is well tolerated, and does not have a sedative effect on the body, which was proven in a randomized trial, which used a placebo. In addition, patients taking this drug, reviews of Mydocalm Richter in injections and tablets left only positive. Only in isolated cases, therapy was ineffective.

Overdose

Overdose cases are extremely rare, since the therapeutic threshold is quite high, and even a dose of 600 mg, as a rule, does not cause signs of an overdose. In the event of shortness of breath, convulsions, suffocation, lack of air, gastric lavage is recommended. There is no antidote therapy.

Price

The price of Mydocalm in tablets of 50 mg is 191 rubles, 150 mg - 222 rubles per package with 30 dragees. It is very important to clarify with the doctor the required dosage and concentration of the substance. The drug is potent, and therefore it is released from pharmacies only by prescription. The medicine should be stored in a dark place, out of the reach of children, at a temperature of 8°-15°C.

Analogues

Sometimes a doctor may prescribe an analogue of Mydocalm, for example, Tolperisone, Tolperisone hydrochloride. Their cost is not much different from the price of Mydocalm. You should be aware that treatment with Mydocalm does not affect the psychological state of patients in any way, does not affect attentiveness when driving a car and performing any work associated with increased danger.

According to the instructions, Mydocalm does not reduce its effect when drinking alcohol.

In combination with niflumic acid, the drug enhances its effect, allowing you to achieve a stronger anti-inflammatory and analgesic effect. When a doctor prescribes this medication additionally, the price of treatment does not increase much, since the cost of niflumic acid is not high.

The treatment of back pain with Mydocalm is quite successful, patients feel immediate relief. In some cases, the doctor may prescribe a second course of taking the drug.

In this article, you can read the instructions for using the drug Mydocalm in different forms ah release. Detailed information about the drug will allow the doctor to select the most rational treatment regimens, and the patient to get acquainted with prices, reviews, analogues, the correctness of taking Mydocalm and other important information.

Compound

The drug Mydocalm (international name in Latin Mydocalm) contains the chemical compound Tolperison hydrochloride (Tolperisonium) as an active substance. Its amount in the composition of the drug depends on the form of release.

As auxiliary components, the manufacturer "Gedeon Richter" (Hungary) introduces substances such as lidocaine (ampoules), ethylene glycols (ampoules), water, derivatives of benzoic, citric and stearic acids (ampoules), Si dioxides, talcs, stearic acid, cellulose, starches, sugars, macrogol, Ti dioxides.

Release form

The medicine is produced in the following forms:

1. Solutions for injections (Mydocalm in ampoules). 1 ml contains Tolperisone 0.1 g and Lidocaine 0.025 g. One package contains 5 ampoules of 2 ml.
2. Coated tablets with dosage of Tolperisone 50 and 150 mg in each tablet. One package contains 30 tablets of the same dosage.

Solution Mydocalm 100 mg is a sterile colorless transparent liquid with a specific odor, ready for administration.

Tablets Mydocalm 50 mg and 150 mg white color, convex on both sides, covered with a glossy shell, on one side there is a notch indicating the dose of Tolperisone 50 and 150, respectively.

pharmachologic effect

Honey drug Mydocalm (INN Mydocalm) belongs to the pharmacological group of muscle relaxants with a central mechanism of action. It has been proven that Tolperisone quickly penetrates into the nervous tissue of the human body, accumulating in certain areas of the brain and spinal cord.

Due to this property, the drug has the main pharmacological actions:

• inhibits the transmission of nerve impulses through the spinal cord to the muscles;
• delays all descending conduction of impulses from the brain;
• reduces the excitability of nerve cells;
• promotes rapid relaxation of skeletal muscles throughout the body, eliminates their spasm;
• eliminates compression of nerve fibers and endings by spasmodic muscles;
• has a local anesthetic effect, since the structure of Tolperisone is similar in chemical structure to Lidocaine.

Active absorption of Tolperisone occurs in the intestine. The bioavailability of the drug is significantly increased when taken against the background of eating a sufficient amount of fatty foods. Excretion of Mydocalm and analogues of this group of drugs is carried out by the kidneys.

Indications for use

According to the official instructions, the indications for the use of different forms of Mydocalm are different.

Tablets Mydocalm 150 mg and 50 mg are used to treat such pathological conditions:

1. Symptomatic and complex treatment of muscle spasms in various pathologies, mainly neuralgia, radiculitis, VVD, spinal hernia, back pain, lumbar osteochondrosis, headaches caused by muscle spasm of the upper shoulder girdle, infectious and inflammatory diseases nervous system.
2. Treatment of post-stroke muscle spasm.
3. Muscle hypertonicity in cerebral palsy, including in childhood.
4. Parkinson's disease in combination with other drugs.
5. Treatment of pathologies caused by spasm of the muscular layer of blood vessels in the organs of vision, as well as in patients with diabetes mellitus.

Mydocalm injection solution is prescribed for such diseases and disorders:

1. Muscle spasms that accompany various pathologies (as for tablets).
2. Muscle spasms after a stroke.
3. Recovery period after operations on the musculoskeletal system.
4. Dystrophic and inflammatory diseases of the joints and muscles (arthritis).
5. Obliterating vascular pathologies, especially of the organs of vision and in patients with diabetes mellitus.

The regimen and duration of the course of treatment is selected by the neurologist, taking into account the severity of the disease.

Contraindications

The main contraindications to the use of Mydocalm Richter include the following:

• sensitivity to active and auxiliary components;
• myasthenia gravis;
• injections - children under 12 years of age;
• tablets - children under 3 years old;
• in the first trimester of pregnancy;
• breast-feeding.

Before you start taking the medication, it is important to identify the presence or absence of these disorders and conditions in which the appointment of the drug is prohibited.

Instructions for use

Solution application

Important! The injection form is not used for children under 12 years of age. It is forbidden to administer the drug on an empty stomach.

Mydocalm is used only intramuscularly in such doses:

• at a normal rate of administration - 100 mg twice a day (one 2 ml ampoule);
• with slow administration - 100 mg once a day (one 2 ml ampoule).

Despite the rather high compatibility of the drug with other drugs, Mydocalm for injection is not allowed to be combined in one syringe and administered without a time interval with other drugs.

The time during which Mydocalm should be injected is selected only by the doctor based on a study of the patient's condition and research data.

Application of the tablet

Important! It is important to take tablets of any dosage only 10 minutes after meals, including fatty ones: in the morning after breakfast, after lunch and in the evening. Drink one glass of clean water. Such methods of application will increase the effectiveness and bioavailability.

For patients with normal kidney and liver function, the daily dose of Mydocalm can be from 150 to 450 mg. The entire amount is divided into three doses in order to achieve a uniform concentration of Tolperisone. The duration of admission is selected only individually, taking into account the severity of the disease and the tolerability of the drug.

With damage to the kidneys, the liver of a moderate degree, Mydocalm is used with caution against the background of constant monitoring of the functioning of the organs and the patient's condition. In severe hepatic and renal pathologies, the use of Tolperisone is not recommended.

Overdose

Tolperisone has a wide therapeutic index - a range of doses, when taken, there are no signs of intoxication and overdose. It was established that taking Mydocalm tablets (according to the Vidal reference book) about 600 mg per day, including in childhood, did not lead to the development of signs of an overdose and did not negative impact on the body. In any case, when taking the drug, it is important to adhere to the therapeutic dosages prescribed by the doctor in both adults and children.

Overdose symptoms are not well understood. It is believed that the most common manifestations and consequences of irrational administration of the drug are the following signs:

• convulsions;
• severe muscle weakness;
• ataxia;
• difficulty in breathing and swallowing movements;
• respiratory arrest (in extremely severe cases, rare);
• severe incontinence of feces and urine due to extreme relaxation of the muscles of the sphincters;
• bouts of vomiting as a manifestation of intoxication.

In case of overdose, only symptomatic treatment is prescribed, including drug withdrawal. There are no drugs (antidotes) that inactivate Tolperisone in the body.

Side effects

Side effects in the process of using Mydocalm rarely develop. In accordance with the description of the studies of the drug and the manufacturer's annotation, three groups of side effects were registered as a result of taking Mydocalm:

1. Infrequent.
2. Rare.
3. Extremely rare.

Uncommon side effects of Mydocalm are as follows:

• weight loss
• sleep disturbance, insomnia;
• headache;
• muscle weakness;
• drowsiness, rapid fatigue;
• decrease in pressure in the vessels;
• dryness of the mucous membranes of the mouth;
• diarrhea;
• minor pain in the abdomen without a clear localization;
• soreness in limbs and muscles.

Rare side effects of Tolperisone:

• allergy to the components of the drug;
• reduced activity;
• depressive state;
• attention disorders;
• convulsions;
• paresthesia;
• severe drowsiness;
• blurred vision;
• sensation of tinnitus;
• tachycardia, pronounced decrease in pressure;
• redness and swelling of the skin;
• shortness of breath, difficulty breathing;
• constipation;
• vomit;
• weakness and discomfort in the limbs;
• flushes of heat;
• strong thirst;
• irritability.

Extremely rare side effects:

• anemia;
• inflammation of the lymph nodes;
• increased appetite;
• violations of consciousness and speech;
• bradycardia;
• chest discomfort;
• osteopenia - a decrease in bone density, an increase in their fragility.

Rarely and extremely rarely, such changes in blood counts are noted:

• increase in the number of leukocytes;
• decrease in the number of platelets;
• an increase in the level of bilirubin;
• increased concentration of creatinine;
• violations of liver enzymes.

As a rule, the drug is well tolerated with the correct selection of the dose and following the recommendations for admission and duration of use.

Interaction with other tools

Groups of drugs that are metabolized in the liver may increase the effectiveness of Tolperisone. These funds include:

If it is necessary to prescribe these drugs together with Mydocalm, it is important to choose the right dose, up to its reduction, so as not to harm the patient, not to provoke manifestations of side effects.

During pregnancy and lactation

Despite the fact that Tolperisone did not show a teratogenic and toxic effect on the fetus, Mydocalm should be taken with caution during pregnancy. In the first trimester, you should refuse to prescribe the drug.

Tolperisone can be excreted in breast milk in small amounts. Therefore, treatment with Mydocalm for breastfeeding(GV) is prohibited to exclude possible negative effects on the child.

With alcohol

The interaction of the drug with alcohol can lead to an increased likelihood of side effects, signs of overdose. Considering that Tolperisone and ethanol are metabolized in the liver, the load on the enzyme system increases, which can significantly reduce the effectiveness of Mydocalm. Therefore, it is recommended to exclude the combined use of Mydocalm and alcohol for the duration of treatment - their compatibility is extremely low and dangerous to health.

Analogues

The list of substitutes (generics) of Mydocalm according to the composition of domestic and foreign manufacturers includes the following drugs:

1. Miaksil.
2. Midostad Combi.
3. Tolperil.

Mydocalm differs from these funds only by the manufacturer and cost. According to important features - pharmacological effects and safety - the drugs do not have a difference.

There are drugs that differ in composition, manufacturers and cost, but have the same pharmacological activity. They can be replaced with each other, since they are all synonyms and analogues of Mydocalm in Russia.

These drugs include:

The replacement of drugs and the selection of Russian analogues of Mydocalm should be carried out only by a doctor.

Best before date

The drug has the same shelf life for all forms of release. It is allowed to store Mydocalm for 3 years from the date of production, which is indicated on the packaging, blister and ampoule. Opened ampoules should not be stored.

Terms of sale and storage

Mydocalm is a prescription drug. To purchase at a pharmacy, you will need a prescription from a doctor, written out indicating the active ingredient in Latin.

Storage conditions of the drug:

• away from children;
• temperature 8-15⁰С for ampoules;
• temperature not higher than 30⁰С for tablets of any dosage;
• away from direct sunlight.

After the expiration date, the drug is not suitable for use.

special instructions

Mydocalm in ampoules is never used for children.

If side effects are detected, including in the form of an allergy, the drug should be discontinued, since anaphylactic shock may develop. After cases of development of allergic reactions, Mydocalm is not re-appointed. If the patient has previously had allergies to drugs, including Lidocaine (in ampoules), then Mydocalm is prescribed with caution, since there is high risk development of a cross form of allergy.

Mydocalm is prescribed with caution when driving vehicles and serious equipment that requires attention and quick response.

Price

Prices for Mydocalm in pharmacies differ depending on the region and form of release.

Mydocalm injection solution for 5 ampoules per package costs from 460 to 705 rubles per package.

Mydocalm tablets 50 mg 30 pieces per pack costs from 284 to 580 rubles per pack.

The price of Mydocalm tablets 150 mg 30 pieces per pack varies from 300 to 680 rubles per pack.

For citation: Parfenov V.A. Back pain and their treatment with Mydocalm // RMJ. 2009. No. 4. S. 267

Back pain occupies one of the leading places among the reasons for seeking medical advice in outpatient practice. Pain is more often localized in the lumbosacral region, less often in the cervical or thoracic region. Acute back pain includes all cases in which the duration of pain does not exceed 6 weeks, subacute - pain from 6 to 12 weeks and chronic - pain from 12 weeks or more. Back pain causes enormous social and economic losses for society due to temporary disability.

Main causes of back pain
Back pain is most often of a muscular origin, it occurs due to muscle strain (for example, unprepared movement) or intense physical activity, which leads to injury of the back muscles, their stretching, to tears of muscle and connective tissue fibers, especially at the points of muscle attachment.
Somewhat less often, back pain is caused by manifestations of osteochondrosis and (or) spondylarthrosis, usually accompanied by reflex muscle tension in the back muscles. Osteochondrosis of the spine includes degenerative lesions of the cartilage of the intervertebral disc with the formation of hernias and reactive changes in the bodies of adjacent vertebrae. Spondylarthrosis is a pathology of the intervertebral (facet) joints caused by degenerative-dystrophic changes or functional blockage of the synovial membrane. Pain due to trauma or muscle strain, as well as pathology of the intervertebral discs or joints, is often regarded as musculoskeletal pain.
Relatively rarely, back pain is caused by compression of the spinal root and its vessels (radiculopathy) due to herniation of the intervertebral disc in the posterior and posterolateral direction, the development of spondylarthrosis with hypertrophy of the intervertebral joints, or the formation of osteophytes.
Back pain can be caused by displacement of the vertebral bodies (spondylolisthesis), vertebral stenosis, instability of the spine, and osteoporosis, more common in menopausal women, complicated by a compression fracture of the spine. The causes listed above, which in the literature are usually regarded as mechanical, account for approximately 90-95% of all cases in outpatient practice.
In more rare cases, back pain is caused by a neoplasm affecting the spine (primary and metastatic tumors of the spine, myeloma), syringomyelia, destruction of the vertebrae and damage to the nerve roots due to infectious processes (osteomyelitis, epiduritis), dysmetabolic disorders (hyperparathyroidism, Paget's disease), fractures spine and some other diseases. Back pain is possible with various somatic diseases ( ischemic disease heart, diseases of the kidneys, pancreas and other organs) by the mechanism of reflected pain.
In the development of chronic back pain, psychosocial factors, the development of depression and (or) anxiety disorder are of great importance, often chronic back pain is a long-term anxiety (somatoform) disorder.
Examination and diagnosis
for back pain
The basis of the diagnosis for back pain is a thorough examination of the patient, including clarification of complaints, history taking, somatic, neurological, manual and orthopedic examinations. Of great importance are manual and orthopedic examinations, which determine mobility in various parts of the spine, range of motion of the upper and lower extremities, the presence of local pain in the back and extremities, muscle tension and pain during their palpation.
When examining a patient with back pain, it is necessary to exclude dangerous diseases, sometimes hiding under the guise of musculoskeletal pathology. The symptoms of "danger" include the following clinical situations:
1) an atypical picture of the pain syndrome (lack of connection of pain with movements of the spine; unusual localization of pain);
2) a history of recent back injury or malignancy;
3) fever, symptoms of intoxication;
4) symptoms of dysfunction of the pelvic bones or lesions of the spinal cord or cauda equina roots;
5) signs mental illness, in which back pain can be its manifestation (somatoform disorder).
In most cases, the diagnosis of back pain is established on an outpatient basis on the basis of somatic, neurological, manual and orthopedic examinations, if they reveal a typical clinical picture of musculoskeletal pathology or radiculopathy in the absence of signs of somatic, oncological or inflammatory disease.
For musculoskeletal pain in the lumbar (lumbalgia), cervical (cervicalgia) and thoracic region (thorocalgia), pain is characteristic that occurs after an awkward (unprepared) movement, intense physical or static load. The pains are usually aching in nature, aggravated by movement with the participation of the interested muscles and (or) parts of the spine, certain poses. The examination reveals limitation of mobility due to increased pain, muscle tension, tenderness on palpation of the muscles and / or the area of ​​the facet joints in the absence of paresis, sensitivity disorders and loss of reflexes.
Discogenic radiculopathy is characterized by sharp shooting pain in the cervical or lumbar region with spread to the fingers or toes. When examining a patient, in addition to changes found in musculoskeletal pathology, sensitive, reflex and, less commonly, motor disorders in the area of ​​the affected root are detected. The lower lumbar and first sacral roots are more often affected, less often the lower cervical and upper lumbar roots.
In most cases, acute back pain does not require additional examinations. If necessary, as additional research methods, X-ray of the spine in several projections, a general blood and urine test, computed x-ray tomography (CT) or magnetic resonance imaging (MRI) of the spine, densitometry, scintigraphy of the pelvic bones and spine are most often used as additional research methods.
X-rays, magnetic resonance imaging (MRI), or X-ray computed tomography (CT) of the spine should not be performed in all patients with back pain. X-ray of the spine is performed to exclude vertebral fractures, inflammatory changes (spondylitis), osteoporosis, primary and metastatic tumors, and other changes. The presence of osteochondrosis and / or spondyloarthrosis according to radiography is found in many middle-aged people and in most elderly patients. This does not rule out the presence of other causes of back pain and may lead to misdiagnosis. X-ray CT or MRI can detect herniated discs, determine their size and location, and detect spinal cord tumor, syringomyelia, and other changes. However, the presence of herniated discs on CT or MRI, especially small sizes, does not rule out another cause of back pain and cannot be the basis of a clinical diagnosis.
Currently, many patients begin their examination not with a doctor's consultation, but with a CT or MRI of the spine. At the same time, the detection of herniated intervertebral discs can cause both a deterioration in their condition (due to an overestimation of the severity of their condition) and improper treatment, in which the “treatment of an intervertebral hernia” comes to the fore, and not the musculoskeletal pathology that actually exists in most patients.
In chronic back pain or frequently recurring back pain, it is important to assess the emotional state, identify increased anxiety and depression, "rental" attitudes to the disease, and psychosocial factors that contribute to the chronic course of back pain.
The course of non-specific pain
in back
In most cases, musculoskeletal pain (lumbalgia, cervicalgia, thorocalgia) disappear within a few days or 2-4 weeks, radiculopathy - within months, but in some cases they take a chronic course for years.
The chronic course of back pain can be facilitated by inadequate treatment of acute pain, prolonged bed rest for acute back pain, excessive limitation of physical activity, a "painful" personality type, low mood, and sometimes the patient's interest in long-term disability, aggravation of existing symptoms, or " rent" attitude to the disease.
Changes in the emotional sphere, various psychosocial factors are one of the common causes of chronic back pain. As psychosocial factors contributing to the frequent exacerbations and chronic course of back pain, there is a desire to receive some kind of financial compensation in connection with the disease, the fear of increased pain and deterioration during physical activity, the hope for various passive methods of treatment (without increasing one's own physical activity). ), job dissatisfaction, depression and anxiety disorders.
Treatment of acute non-specific (musculoskeletal) back pain
Medical tactics for acute nonspecific back pain is, on the one hand, to relieve pain and return the patient to an active lifestyle as quickly as possible, and, on the other hand, to prevent repeated exacerbations and chronic pain syndrome.
It is advisable to inform the patient about the benign nature of his disease and the high probability of its rapid resolution. It is necessary to avoid overexertion and excessive stress on the spine and muscles (for example, prolonged sedentary work). Bed rest is not recommended, on the contrary, it slows down recovery and negatively affects the patient's rehabilitation process, it is recommended to return to normal activities faster.
Analgesics (paracetamol), non-steroidal anti-inflammatory drugs (NSAIDs), and muscle relaxants are used to relieve pain. For acute pain, it is advisable to treat at home, without forcing the patient to visit the clinic for injections or physiotherapy, the benefits of which are doubtful.
For back pain, NSAIDs are often used, which have a good analgesic effect and a pronounced anti-inflammatory effect. Diclofenac, indomethacin, piroxicam, naproxen, ibuprofen and other drugs are used as NSAIDs. The average therapeutic doses of diclofenac are 50-100 mg for oral administration or in the form of rectal suppositories, the maximum daily dose is 150 mg orally, intramuscular administration of the drug is used to achieve a rapid effect. As NSAIDs that have selective inhibition of cyclooxygenase-2 and usually have fewer side effects, you can use meloxicam (usually 15 mg / day in 1-2 doses) or celecoxib, usually 200 mg / day. in one or two doses.
Muscle relaxants reduce pain, reduce reflex muscle tension. Treatment with muscle relaxants begins with the usual therapeutic dose and continues for as long as the pain persists. A meta-analysis of the use of muscle relaxants in acute low back pain shows that they are most effective when prescribed from the onset of pain, their addition to NSAIDs can reduce the duration of the disease. In Russia, Mydocalm and tizanidine are commonly used as muscle relaxants for back pain.
Locally with back pain, you can use rubbing ointments, compresses with a 30-50% solution of dimexide and novocaine. The widespread use of back muscle massage, ultrasound treatment methods, electrotherapy, traction is not recommended, since their effectiveness has not been proven, and their administration can contribute to the formation of a “painful” personality, chronic pain.
With pain relief, a gradual increase in motor activity, muscle strengthening exercises are recommended. However, there is no special therapeutic gymnastics that allows you to achieve a faster disappearance of pain. A meta-analysis of 10 studies examining the effectiveness of various methods of therapeutic exercises did not show any advantages in terms of either immediate or long-term treatment outcomes.
Treatment of chronic
non-specific
(musculoskeletal) back pain
In the chronic course of back pain, therapeutic exercises, physiotherapy, NSAIDs, muscle relaxants, antidepressants, manual therapy and psychotherapeutic methods of treatment can be effective. The most important of these are therapeutic exercises, the "education" of patients, in which patients are explained the need to maintain sufficient physical activity, but to avoid excessive physical and static loads, wearing weight. Among psychotherapeutic methods, the positive impact of cognitive-behavioral psychotherapy is noted.
Many patients with chronic back pain show signs of depression, so a significant benefit can be obtained from the use of antidepressants. In cases where there are no signs of depression, the effectiveness of antidepressants is not so high. Of great importance is the professional, social and domestic rehabilitation of patients, their gradual return to normal (before the onset of pain) activities.
Traditionally in our country, manual therapy is widely used for chronic back pain. different kinds physiotherapy treatment, in some centers - spinal traction. Many patients are observed and treated only by manual therapy specialists for a long time. A positive effect can be obtained from manual therapy if it is performed at a high methodological level and combined with therapeutic exercises and other methods of treatment. The question of the effectiveness of most physiotherapeutic methods of treatment, reflexology remains debatable, and spinal traction often leads to deterioration. Wearing a lumbar fixation belt or cervical collar is not effective for long-term use, they can be used periodically if long-term movement is necessary, as well as when lifting weights.
Surgery (removal of a herniated disc) is not required for most patients if the pain is of musculoskeletal origin. Surgical treatment is discussed in case of long-term (more than 3-4 months) musculo-tonic syndrome caused by a herniated disc, and the absence of the effect of conservative treatment.
As a prevention of back pain recurrence, provoking factors should be avoided (lifting large loads, staying in an uncomfortable position for a long time, intense physical activity, carrying a heavy bag in one hand, etc.), use walking, regularly engage in swimming or therapeutic exercises.
Mydocalm in the treatment of back pain
The use of Mydocalm, as well as other muscle relaxants, is justified by the important role of muscle spasm in the pathogenesis of nonspecific (musculoskeletal) back pain. Pain of various origins (due to damage to the muscles themselves, the facet joints of the spine, intervertebral discs) increases the activity of the motor neurons of the spinal cord, which leads to muscle spasm, which, in turn, plays a significant role in maintaining the pain itself. Pathologically increased muscle tone has various mechanisms for increasing pain: direct irritation of muscle pain receptors, deterioration of blood supply to the muscles, which leads to the formation of a vicious circle leading to increased muscle spasm and accompanying pain. Muscle relaxants break the vicious cycle of "pain > muscle spasm > pain" and, as a result, can accelerate the healing process.
Mydocalm (tolperisone) has a predominantly central muscle relaxant effect, it stabilizes cell membranes. A decrease in muscle tone when taking the drug is associated with a depressing effect on the caudal part of the reticular pharmacy, suppression of spinal reflex activity. The drug also has a moderate central analgesic effect and a slight vasodilating effect. Mydocalm is usually administered orally at 150 mg 2 or 3 times a day, it is well tolerated even by elderly patients, it can be used in combination with various drugs.
Over the past 10 years, several double-blind, placebo-controlled studies have been conducted that have shown the efficacy and safety of Mydocalm in acute and chronic back pain.
The efficacy and safety of Mydocalm for back pain of muscular origin was shown in a double-blind, placebo-controlled study in 110 patients aged 20 to 75 years. In 8 study centers, patients received Mydocalm at a dose of 300 mg per day or placebo in combination with therapeutic exercises and rehabilitation for 21 days. Both groups were dominated by patients with chronic (more than 3 months) pain syndrome. The main criterion for the effectiveness of treatment is pain threshold pressure measured with special device(Pressure Tolerance Meter) at 16 symmetrical points of the trunk and limbs. The results of the study showed that the use of Mydocalm significantly more than placebo reduces the sensation of pain. The difference between the treatment and placebo groups was noted already on day 4, it gradually increased and became statistically significant on days 10 and 21 of treatment, which were chosen as endpoints for evidence-based comparison.
Mydocalm does not cause sedation and muscle weakness when taken, which was proven in another double-blind, placebo-controlled study in which 72 healthy volunteers participated. Volunteers randomized to placebo or 150 or 450 mg of Mydocalm per day in three divided doses for eight days. The results of the study showed that there are no differences in the speed of reactions and other neuropsychological tests after 1.5 hours, 4 hours, 6 hours and eight days after taking Mydocalm or placebo.
One of the latest double-blind, placebo-controlled studies showed the effectiveness of Mydocalm in patients with acute non-specific low back pain. The study included 225 patients aged 18 to 60 years, in whom lumbar pain appeared no earlier than 5 days before the start of the study. When examined on the 7th day of treatment in the Mydocalm treatment group, there was a significant advantage in assessing the quality of life of patients, and this positive trend continued until the end of the study. In the Mido-cal-mo group, there was also a trend towards a reduction in the time of incapacity for work.
We noted the effectiveness of Mydocalm in patients with acute lumbar pain (no more than 7 days from the moment of illness) of working age, some turned to a neurologist for advice in one of the Moscow polyclinics. Within four months, the study included 60 patients (43 women and 17 men) aged 18 to 60 years (mean age 41.8 years) with acute low back pain. All patients took NSAIDs, in addition, 30 patients additionally took Mydocalm 150 mg 3 times a day (Mydocalm treatment group), the remaining 30 patients made up the comparison group. During treatment, all patients recovered and were discharged to work in a satisfactory condition. However, the average length of stay on sick leave in the group of patients treated with Mydocalm was 10.3±1.0 days and was significantly lower than in the comparison group, in which it reached 17.7±3.3 days (p<0,05).
Thus, back pain is most often of musculoskeletal origin. In their diagnosis, careful collection of complaints and anamnesis, somatic, neurological, manual and orthopedic examinations are of key importance. Radiography, CT and MRI of the spine are used largely to exclude other diseases that can occur under the guise of benign musculoskeletal pain. In the case of non-specific (musculoskeletal) back pain, the patient should be informed about the favorable prognosis of the disease, analgesics and NSAIDs should be used to reduce pain. The inclusion of muscle relaxants in therapy can lead to a faster recovery and a decrease in the period of temporary disability. The effectiveness of the muscle relaxant Mydocalm is indicated for acute and chronic back pain, its important advantages are good tolerability, the absence of a sedative effect. To prevent the chronic course of lumbar pain and their repetition, an active lifestyle, avoidance of lifting significant weights and static overloads, and therapeutic exercises are recommended.

Literature
1. Bogacheva L.A., Snetkova E.P. Back pain: clinic, pathogenesis, principles of management, principles of management (experience of the outpatient department of back pain). // Pain, 2005, No. 4, p. 26-30.
2. Gurak S.V., Parfenov V.A., Borisov K.N. Mydocalm in the complex therapy of acute lumbar pain // Pain. - 2006. - No. 3. - S. 27-30.
3. Laszlo H., Melinda M., Zsolt S., Istvan Z. Treatment of acute low back pain with Mydocalm. Results of an international multicenter, randomized, double-blind, placebo-controlled clinical trial. Russkiy med. magazine 2003, no. 5, p. 246-249.
4. Podchufarova E.V., Yakhno N.N. Pain in the back and limbs. In: Diseases of the nervous system. Guide for doctors. Edited by N.N. Yakhno. - M., 2005, volume 2, p. 306-331.
5. Bogduk N., McGuirk B. Medical management of acute at chronic low back pain. - Amsterdam: Elsevier, 2002
6. Burton A.K., Balague F., Cardon G. et al., for the COST B13 Working Group on European Guidelines for Prevention in Low Back Pain. How to prevent low back pain // Best Pract Res Clin Rheumatol 2005;19:541-555.
7. Chou R., Huffman L.H. Nonpharmacologic therapies for acute and chronic low back pain: a review of the evidence for an American Pain Society/American College of Physicians clinical practice guideline. // Ann Intern Med 2007;147: 492-504.
8. Dugan S.A. The role of exercise in the prevention and management of acute low back pain // Clin Occup Environ Med. 2006 - Vol. 5. - P. 615-632.
9. Dulin J., Kovacs L., Ramm S. et al. Evaluation of sedative effects of single and repeated doses of 50 mg and 150 mg tolperisone hydrochloride. Results of a prospective, randomized, double-blind, placebo-controlled trial // Pharmacopsychiat. - 1998. - Vol. 31. - P. 137-142.
10. Carragee E.J. clinical practice. Persistent low back pain. // N Engl J Med 2005;352: 1891-1898.
Hayden JA, van Tulder MW, Malmivaara A, Koes BW. Exercise therapy for treatment of non-specific low back pain. // Cochrane Database Syst Rev 2005;(3):CD000335.
11. Pratzel H.G., Alken R.-G., Ramm S. Efficacy and tolerance of repeated doses of tolperisone hydrochloride in the treatment of painful reflex muscle spasm: results of a prospective placebo-controlled double-blind trial // Pain. - 1996. - Vol. 67. - P. 417-425.
12. Russo R.B. Diagnosis of low back pain: role of imaging studies // Clin Occup Environ Med. 2006 - Vol. 5. - P. 571-589
13. Shen FH, Samartzis D, Andersson GB. Nonsurgical management of acute and chronic low back pain // J Am Acad Orthop Surg. 2006 - Vol. 8. - P. 477-487.
14. van Tulder M.W., Touray T., Furlan A.D. et al. Muscle relaxants for non-specific low back pain. // Cochrane Database Syst Rev 2003;(2):CD004252.
15. van Tulder M., Becker A., ​​Bekkering T. Et al. European guidelines for the management of acute nonspecific low back pain in primary care // Eur Spine J. 2006- Vol. 15. (Suppl. 2): S.169-S.191.
16. Waddel G. The back pain revolution. Churchill Livingstone. 1998.

Mydocalm is actively used to treat spastic lesions of the skeletal muscles in patients with damage to the central nervous system, as well as in patients with spinal pathology. Mydocalm for lower back pain helps to reduce spasm of the back muscles, which helps to reduce compression of the nerves or blood vessels, which is the cause of the pain syndrome.

Mydocalm is a muscle relaxant with a central action. This drug is included in the complex therapy of diseases of the spine (cervical, thoracic, osteochondrosis, radiculopathy, vertebral hernia).

Compound medicinal product helps to relieve spasms of the back muscles, which reduces the compression of nerves or blood vessels.

According to the official instructions, Mydocalm is produced in the form of tablets (50 mg, 150 mg of Tolperisone hydrochloride) and ampoules (1 ml - 100 mg of Tolperisone hydrochloride, 2.5 mg of Lidocaine hydrochloride).

The injection form of the drug is intended for intravenous or intramuscular administration of the drug.

Mechanism of action of Mydocalm:

· myasthenia gravis;

The drug is part of the treatment of diseases of the spine. Mydocalm helps to relax the muscles of the back, improves blood flow in the spine due to the expansion of the arteries. In combination with Mydocalm, non-steroidal anti-inflammatory drugs (NSAIDs) are also often used.

Tolperisone hydrochloride allows you to reduce the dosage of NSAIDs by reducing the pressure on the nerve or vessel. Injections with a muscle relaxant reduce pain, as they contain Lidocaine. With back pain, you can also drink Mydocalm in tablets.

Mydocalm from the back with injections:

With the complex therapy of osteochondrosis, cerebral circulation improves, pain syndrome disappears. Patients note a decrease in headaches, lumbago. Radiculopathy is also effectively treated with a muscle relaxant.

In patients, the back hurts less, the inflammation goes away faster. With intervertebral hernia, pain causes compression of the formation. Tolperisone hydrochloride reduces pressure on the hernia, which also causes a decrease in pain.

A muscle relaxant is actively prescribed by therapists for the treatment of back pain. Mydocalm for osteochondrosis, radiculopathy, as well as other pathologies of the spinal column, alleviates the condition of patients, quickly eliminates pain, and reduces the concentration of NSAIDs.

The drug received a large number of reviews from patients and doctors. It is necessary to use the medicine strictly according to the doctor's prescription, as it has its own contraindications. The right approach to treatment will reduce the frequency of exacerbations of back diseases.

Be sure to check out these articles:

The main symptom of osteochondrosis is pain. It is present in almost all stages of the disease. The intensity of the pain syndrome depends on the prevalence and degree of pathological changes in the tissues of the intervertebral discs and vertebrae, the tension of the muscle fibers, the neglect of the inflammatory process, and a number of other factors. One of the main ways to treat osteochondrosis is drug therapy. Unfortunately, not all of the prescribed funds are highly effective. The action of local preparations (ointments, gels) mainly leads to a limited local effect, and many of the oral drugs do not affect the cause and cannot eliminate the inflammatory process. In the treatment of osteochondrosis, Mydocalm has proven itself well.

Muscle spasm compresses blood vessels

What is the danger of muscle spasm? In addition to provoking pain, contraction of muscle fibers can lead to a number of serious consequences.

1. The main possible result of a spasm is squeezing of the blood vessels. Compression of blood vessels leads to impaired blood circulation. This phenomenon is especially dangerous when cervical osteochondrosis, since its result is a violation of cerebral circulation, insufficient supply of certain parts of the brain with nutrients and oxygen. The use of Mydocalm in this form of osteochondrosis is of great importance, since it helps to prevent the development of formidable complications.
2. Another consequence of muscle spasm is the compression of nerve endings, which provokes the occurrence of severe pain of a radiating nature. In addition, the work of internal organs innervated by injured fibers may be disrupted.

Preparations of this group are used to relieve muscle tension in pathological lesions of the spine, including osteochondrosis.

Mydocalm relieves muscle tension

The best way to get rid of spastic pain is centrally acting muscle relaxants, i.e. directed directly at the parts of the central nervous system responsible for the regulation of muscle tone. Mydocalm also belongs to this group.

The results of numerous studies show that when muscle relaxants are added to the standard treatment regimen for osteochondrosis based on non-steroidal anti-inflammatory drugs, analgesics, physiotherapy procedures and massage, it is possible to significantly increase the effectiveness of therapy, achieve relief or reduction of pain in a short time and increase the mobility of the damaged spinal column.

The use of Mydocalm in osteochondrosis has a number of obvious advantages:

Tablets Mydocalm

• The central muscle relaxant effect it has is highly selective. The drug reduces the degree of excitability of muscle fibers, but it does not have an overwhelming effect on nerve impulses, due to which the necessary muscle strength is provided during movement and correct posture is maintained.
• Even with prolonged use, Mydocalm is well tolerated and does not lead to dangerous side effects.
• Treatment with this muscle relaxant does not affect the patient's activity, does not reduce his physical and mental capacity for work.
• Mydocalm fits perfectly into the traditional scheme for the treatment of osteochondrosis of the cervical, thoracic or lumbar regions and is combined with other used drugs.
• Due to the pronounced muscle relaxant and analgesic effect provided by the drug, it is possible to reduce the dosage of non-steroidal anti-inflammatory drugs. As a result, their negative side effect on the internal organs is eliminated, while the effectiveness of the treatment of osteochondrosis is not reduced at all.

Currently, Mydocalm is considered the most effective and safe of the existing muscle relaxants. It has been used in clinical practice for over 50 years.

Mydocalm is used to treat neurological syndromes, accompanied by pain, increased muscle tone and trophic disorders.

The active substance of the drug has a local anesthetic and membrane-stabilizing effect. With osteochondrosis and other diseases Mydocalm:

Mydocalm contains lidocaine

• helps to eliminate muscle tension;
• leads to an indirect analgesic effect;
• dilates blood vessels;
• improves blood circulation and lymph flow.

Reviews of specialists and patients testify to the rapid action of Mydocalm and its good tolerability.

The drug is available in the form of round film-coated tablets. Tablets with the engraving "50" contain 50 mg of the active substance - tolperisone hydrochloride, in tablets with the engraving "150" of the active substance, respectively, three times more. The following are used as auxiliary components in Mydocalm:

• citric acid monohydrate;
• stearic acid;
• microcrystalline cellulose;
• silica;
• macrogol 6000;
• titanium dioxide;
• lactose monohydrate;
• dye.

Mydocalm in the form of a solution for injection is released in darkened ampoules. Each ampoule contains:

• tolperisone - 100 mg;
• lidocaine hydrochloride - 2.5 mg.

As auxiliary components, in addition to the above substances, the following are used:

• iron oxide black;
• iron oxide red;
• iron oxide yellow.

Mydocalm is taken for diseases of the spine

With osteochondrosis of any localization (cervical, thoracic, lumbar), Mydocalm is prescribed in the presence of reflex and compression syndromes. The drug eliminates muscle rigidity and pathological high muscle tone. As a result, pain is reduced and stiffness of movements is reduced.
In addition to osteochondrosis, the drug is prescribed to relax skeletal muscles also in some other pathologies of the musculoskeletal system:

• spondylosis;
• spondylarthrosis;
• lumbar and cervical syndromes;
• arthrosis of large vessels.

Mydocalm is prescribed for cerebral palsy, some other encephalopathies, accompanied by muscular dystonia.
The drug is also indicated for a pathological increase in tone and the presence of muscle spasms, which are the result of neurological diseases of an organic nature:

1. myelopathy;
2. multiple sclerosis;
3. encephalomyelitis, etc.

Mydocalm is also used after surgery for osteochondrosis, other orthopedic and traumatological surgical interventions.

The drug is taken three times a day

With osteochondrosis and other diseases, Mydocalm is not recommended for use in:

• hypersensitivity to tolperisone;
• allergies to lidocaine.

The drug is prescribed with caution in childhood. It is not recommended for babies under 1 year of age.

In osteochondrosis, the dose of Mydocalm is determined individually, depending on several factors:

• features of the clinical picture and its severity;
• localization of the lesion (in the cervical, thoracic or lumbar region);
• patient's age;
• the presence of comorbidities.

As a rule, adults are prescribed a three-time intake of Mydocalm (50 mg each). With severe spasms and severe osteochondrosis, it is possible to increase the dosage three times (three tablets three times a day after meals).

Children take Mydocalm in tablets of 50 mg.

Mydocalm is prescribed for children in tablet form of 50 mg. The daily dose should be divided into three parts. It is calculated according to the following scheme:

• for patients under 6 years old - 5 mg per 1 kg of weight;
• for children from 7 to 14 years old - 2-4 mg per 1 kg of weight.

If the tablet is difficult for the child to swallow, it should be crushed.

The action of the drug begins 40 minutes after ingestion. The recommended course duration is no more than 10 days.

Intramuscular injections: 200 mg/day. Divided into two doses.

Intravenous injection: 100 mg/day.

Mydocalm is compatible with other medications used for osteochondrosis of the spine. In any case, there are no data confirming the manifestation of a negative effect from the simultaneous use of the drug with other drugs. It is prescribed simultaneously with anti-inflammatory, analgesic, sedative, hypnotic drugs.

The only point that needs to be taken into account: Mydocalm is able to enhance the effect of niflumic acid.

The use of Mydocalm in osteochondrosis in pregnant women is indicated only in case of emergency. This is especially true for the first trimester. The tool is also not recommended for lactation, during breastfeeding.

During pregnancy, Mydocalm is undesirable

According to reviews, taking Mydocalm for osteochondrosis does not lead to serious undesirable effects. When they occur, the dosage is reduced. Possible side effects include:

• nausea, sometimes with vomiting;
• feeling of discomfort in the abdomen;
• headache;
• lowering blood pressure (possible with rapid intravenous administration);
• muscle weakness;
• allergic reactions: pruritus, erythema, urticaria, bronchospasm, angioedema, anaphylactic shock.

Reviews of patients diagnosed with osteochondrosis who have taken or are taking Mydocalm prove the effectiveness and safety of the remedy.

I met Mydocalm two years ago. It was recommended to me by my doctor. At that time, I was simply writhing in pain, I could neither sit nor stand. A few injections literally brought me back to life. And - most importantly - the effect lasts for a long time. Now, as soon as osteochondrosis makes itself felt, I take Mydocalm tablets. Andrey, St. Petersburg.

Mydocalm helped my husband a lot. The last time he had an acute attack of lumbar osteochondrosis, neither Movalis nor Nimesil helped. Ointments were also useless. Then the doctor recommended a course of treatment with Mydocalm. It cannot be said that her husband's back does not hurt at all after this, but there have been no acute attacks for a long time. Elena, Yekaterinburg.

Mydocalm is actively used to treat spastic lesions of the skeletal muscles in patients with damage to the central nervous system, as well as in patients with spinal pathology. Mydocalm for lower back pain helps to reduce spasm of the back muscles, which helps to reduce compression of the nerves or blood vessels, which is the cause of the pain syndrome.

Mydocalm is a muscle relaxant with a central action. This drug is included in the complex therapy of diseases of the spine (cervical, thoracic, osteochondrosis, radiculopathy, vertebral hernia). The drug helps to relieve spasms of the back muscles, which reduces the compression of the nerves or blood vessels.

According to the official instructions, Mydocalm is produced in the form of tablets (50 mg, 150 mg of Tolperisone hydrochloride) and ampoules (1 ml - 100 mg of Tolperisone hydrochloride, 2.5 mg of Lidocaine hydrochloride). The injection form of the drug is intended for intravenous or intramuscular administration of the drug.

Mechanism of action of Mydocalm:

• inhibits the penetration of potassium ions, as well as other substances through the membranes of nerve cells;
• relaxes peripheral striated skeletal muscles;
• reduces the reflex response of neurons in the brain stem;
• dilates peripheral vessels;
• interferes with the activity of adrenergic receptors in synaptic connections.

spastic lesions of the muscles of the central genesis ( multiple sclerosis, cerebral ischemia);

spondylarthrosis, spondylosis, osteochondrosis, radiculopathy;

recovery after surgical procedures (orthopedics);

cerebral palsy (spastic), brain pathology with muscular dystonia;

children under 3 years of age (tablet form), up to 18 years of age (injectable);

Intolerance to the components of the drug;

The drug is part of the treatment of diseases of the spine. He promotes relaxation of the back muscles, improves blood flow in the spine due to the expansion of arteries. In combination with Mydocalm, non-steroidal anti-inflammatory drugs (NSAIDs) are also often used. Tolperisone hydrochloride allows you to reduce the dosage of NSAIDs by reducing the pressure on the nerve or vessel. Injections with a muscle relaxant reduce pain, as they contain Lidocaine. With back pain, you can also drink Mydocalm in tablets.

50-150 mg, 2-3 times a day.

2-4 mg per kg of body weight (in 3 divided doses per day).

5 mg per kg of body weight (daily dose is divided into 3 times).

For back pain, Mydocalm should be taken after meals, washed down with 200 ml of water.

Mydocalm from the back with injections:

• intramuscularly (1 ml, 2 times a day);
• intravenously (1 ml, 1 time per day).

With the complex therapy of osteochondrosis, cerebral circulation improves, pain syndrome disappears. Patients note a decrease in headaches, lumbago. Radiculopathy is also effectively treated with a muscle relaxant. In patients, the back hurts less, the inflammation goes away faster. With intervertebral hernia, pain causes compression of the formation. Tolperisone hydrochloride reduces pressure on the hernia, which also causes a decrease in pain.

A muscle relaxant is actively prescribed by therapists for the treatment of back pain. Mydocalm for osteochondrosis, radiculopathy, and other pathologies of the spinal column alleviates the condition of patients, quickly eliminates pain, and reduces the concentration of NSAIDs. The drug received a large number of reviews from patients and doctors. It is necessary to use the medicine strictly according to the doctor's prescription, as it has its own contraindications. The right approach to treatment will reduce the frequency of exacerbations of back diseases.

Vidal: https://www.vidal.ru/drugs/mydocalm__31619
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BACKGROUND

Today is my review of Mydocalm. Yes, it is again dedicated to pills and. pain. I think everyone knows the state severe pain when you literally can't move. And those who are familiar with the manifestations of osteochondrosis and other “joyful” diseases of the spine know that this pain simply turns life into existence. Lying existence.

Thanks to genetics, I am the owner of unstable vertebrae, joints, muscles. It seems to be fun: a good stretch, splits, bridges. As my neurologist says, no matter how much you rot, a flexible branch will not break. But on the other hand, thanks to this, I got cervical osteochondrosis and even protrusion of the intervertebral disc in the lumbosacral region.

These two miraculous diseases give indescribable sensations. For more than a year, with a frequency of once a month, or even more often, exacerbations occur, the back hurts both at rest and when moving. It hurts so much that all the few days of exacerbation I move almost crawling like a turtle. It hurts, and it's funny: at 25, walking like a crooked apricot.

The diagnosis after long torments (mine and doctors) was put on the basis of MRT. And finally, I was given treatment!

One of the main principles of treatment is to relieve pain and relieve muscle inflammation. I was sent to a chiropractor and strictly ordered to be friends with him for the rest of my life. And medication was prescribed to be taken only for the period of exacerbations.

1. Non-steroidal anti-inflammatory and painkillers (Ibuprofen, Nise, Nimesil, etc.)

2. B vitamins (I used Milgamma)

3. Muscle relaxants to relieve muscle spasm and relieve pain.

In my case - Mydocalm.

Mydocalm belongs to the pharmacotherapeutic group “ Centrally acting muscle relaxants ” and is a drug that helps reduce the tone of skeletal muscles.

In addition, the drug acts as a local anesthetic, and also inhibits the conduction of nerve impulses in the primary afferent (from the Latin “afferens” - bringing) nerve fibers And motor neurons - nerve cells , responsible for carrying information to effectors (usually muscles) from CNS .

almost 400 rubles for 30 tablets. The package includes 3 blisters of 10 tablets.

Indications for the appointment of Mydocalm are:

• pathologically increased muscle tone and spasms of skeletal (striated) muscle tissue, which are the result of organic lesions CNS , including including multiple sclerosis , encephalomyelitis , stroke brain, etc.;
• myogenic contractures, increased muscle tone and spasticity due to diseases of the musculoskeletal system ( love with sciatica , spondylosis affecting large joints arthrosis ,cervical syndrome etc.);
• non-inflammatory diseases of the brain accompanied by disorders of muscle tone ( cerebral palsy );
• cholelithiasis ;
• strongly pronounced pain syndrome , noted against the background of development hemorrhoids ;
• menstrual pain syndrome ;
• risk of spontaneous interruption pregnancy due to an increase in the tone of the uterine muscle structures;
• renal colic .

They have a wide range of applications, before taking I read reviews about the drug, and many take it even with a headache. True, more and more often people complain that the drug does not save from a headache, but they also prescribe it to themselves. I believe that such drugs for nothing without a doctor's prescription can not be taken.

The mysterious phrase in the instructions was very amused:

The mechanism of action of the drug is not fully understood.

That is, it will help you, but how and why, we have no idea)

MYDOCALM FOR OSTEOCHANDROSIS

Why are muscle relaxants prescribed for osteochondrosis?

Developing at osteochondrosis pain syndrome provokes a compensatory spasm of the deep layers of the back muscles. And this, in turn, causes myopically spinal column and limited mobility of the spinal motion segments.

The consequence of such a muscular-tonic imbalance is a deterioration in the course of the disease and a decrease in the therapeutic effectiveness of all measures taken.

Muscle relaxants at osteochondrosis assigned to correct this imbalance. Drugs from this pharmacotherapeutic group:

• have a sedative effect;
• relieve symptoms pain syndrome ;
• suppress spinal reflexes;
• relieve muscle tension.

MODE OF APPLICATION

Mydocalm should be taken after a meal (15-20 minutes after a meal), with a small amount of liquid.

Children from 3 to 7 years old are prescribed at the rate of: 5 mg of the drug per 1 kg of body weight, at the age of 7 to 14 years - 3 mg / kg. The resulting dosage is divided into three parts and taken orally during the day.

Adults and children from the age of 14 should start taking 100 mg per day (50 mg in two divided doses). The daily dose is gradually increased to 150 mg.

I was prescribed 50 mg. 3 times a day, if the drug copes with this dosage, the dose can not be increased. 50 mg is enough for me.

The doctor immediately warned that it should be taken only during the period when the pain bothers, then the drug is canceled.

For treatment osteochondrosis accept muscle relaxants recommended for very short courses. Given the abundance of side effects, practitioners are very careful to include these drugs in their patients' regimens.

EFFICIENCY

At the first dose, the drug helped after two days, with subsequent exacerbations - after one tablet. It's like some kind of magic: here you can't straighten up, you take a pill - vzhuh, and you flutter.

It is not necessary to drink more than two or three tablets for one exacerbation. I consider this to be a very good result.

SIDE EFFECTS

Taking the drug with individual hypersensitivity can cause weakness in the muscles, dyspeptic phenomena (nausea, discomfort and vomiting), as well as headaches. With a rapid intravenous infusion of the solution, a decrease in blood pressure is possible. With individual intolerance to the drug, allergic reactions develop. As a rule, with a decrease in the dose of the drug side effects pass very quickly.

I experienced only one side effect: muscle weakness.

After taking even one or two tablets, physical strength seems to decrease. At first I did not attach any importance to this, then I compared the intake of pills with the consequences. Once, the next day after taking it, with some ordinary movement of my arm, I had a painful crack in my shoulder joint, it felt like I had dislocated it. Everything worked out, but the joint hurt for another week. The doctor said it was a normal reaction. Now I take Mydocalm with caution.

CONTRAINDICATIONS

The drug is good in complex therapy to relieve pain. Of course, it must be prescribed by a doctor, and if you have been prescribed this drug, feel free to take it. He will help.

Thank you for your attention! Be healthy!

My other reviews on medical procedures and medications:

·٠ ● Moles: remove (,) cannot (,) leave ● ٠·

·٠ ● UNIVERSAL Polysorb: for hair, sunburn and weight loss ● ٠·

Degenerative processes in the spine require complex treatment, one of the components of which are drugs of various effects. Mydocalm in osteochondrosis is used to eliminate pain, it is prescribed to patients in combination with anti-inflammatory drugs.

The neurology clinic of the Yusupov hospital offers a comprehensive diagnosis and treatment of osteochondrosis. Experienced neurologists prefer sparing procedures and influences. So, the drug mydocalm for cervical osteochondrosis is prescribed with physiotherapy exercises and physiotherapy.

Mydocalm is a myorexalant that relieves muscle hypertonicity and spasms. As a result of the use of the drug in the damaged section, mobility decreases and the pain syndrome decreases. Mydocalm for cervical osteochondrosis, lesions of the lumbar and thoracic increases the effectiveness of procedures and allows you to achieve positive result in the minimum time.

Mydocalm is produced as a solution for injection, in the form of tablets. Tolperisone is the main active ingredient. The drug for intramuscular, intravenous administration is available in the form of 1 ml ampoules, which contain lidocaine - 2.5 mg hydrochloride tolperisone - 100 mg. Mydocalm tablets are packed in 10 pcs. in one blister.

Auxiliary substances that are part of the drug are:

• stearic acid;
• silica;
• citric acid monohydrate;
• macrogol 6000;
• cellulose;
• lactose monohydrate;
• dye.

In the treatment of osteochondrosis of the spine in the Yusupov hospital, an individual comprehensive program is developed for patients, aimed at eliminating the signs of the disease, stopping the pathological process and restoring mobility.

Muscle spasm in osteochondrosis provokes the development of pain, which is the most common symptom of the disease. In addition, as a result of spasm, compression of blood vessels and circulatory disorders can occur. Mydocalm with cervical osteochondrosis and the pathological process in other departments quickly relieves spasms.

Numerous clinical studies conducted by specialists prove the effectiveness of the drug and absolute safety. Mydocalm is combined with the use of non-steroidal anti-inflammatory drugs, which allows you to limit yourself to the minimum dosage to eliminate symptoms and the inflammatory process.

Mydocalm has an indirect analgesic effect, and also improves blood flow and outflow of lymphatic fluid in the affected spine. The use of the drug with physiotherapy exercises, massages and physiotherapy increases the effectiveness of these effects.

Neurologists at the Yusupov Hospital use predominantly conservative methods of treating osteochondrosis. Close cooperation with general practitioners, rehabilitologists, exercise therapy instructors allows you to influence not only the underlying disease, but also eliminate concomitant pathologies.

If a patient is prescribed mydocalm for osteochondrosis, the release form and dosage are determined by a neurologist. The specialists of the neurology clinic of the Yusupov hospital, when prescribing a medicine, are guided by the results of the examination and the individual characteristics of the patient.

The daily norm of mydocalm for adults can be 50 mg (one tablet) three times a day. With an exacerbation of the disease, the dosage may be increased by the attending physician. The duration of taking the drug should not exceed 10 days.

Neurologists at the Yusupov Hospital in the treatment of osteochondrosis include in the treatment program measures aimed at eliminating the main symptoms of the disease, eliminating negative factors and excessive loads on the damaged segment of the spine, stimulation muscle activity.

In the neurology clinic of the Yusupov hospital, you can undergo treatment for osteochondrosis according to an individual program, which may include mydocalm for cervical osteochondrosis, exercise therapy, massages and other procedures.

The staff of the clinic ensures the most comfortable stay of patients. Modern material and technical equipment of a medical institution makes it possible to detect the disease on early stage which is the key to successful treatment. For the convenience of patients, an appointment with specialists is carried out by calling the Yusupov Hospital.

The use of Mydocalm in osteochondrosis is due to its analgesic effect. The cervical type of the disease and lesions of the lumbar spine cause pinched nerves, which leads to the appearance of pain and the formation of pathologies. As a result of the action of the disease, the load from the vertebrae is transferred to the muscles. The cervical region is not able to withstand it, which leads to spasms.

Muscle relaxants act on the brain. As a result, the organ gives signals to reduce muscle tension.

The result of treatment of osteochondrosis with Mydocalm:

• relieving muscle tension;
• the appearance of an analgesic effect;
• expansion of blood vessels;
• normalization of blood circulation and metabolism.

You can take Mydocalm for osteochondrosis both in the initial stages and in the acute phase of the disease. The agent is fast-acting and well tolerated.

With osteochondrosis, radiculopathies, it is impossible to stop an attack of spastic pain without muscle relaxant antispasmodics.

In the acute period, injectable forms of muscle relaxant preparations are indicated for treatment. Most often, vertebrologists prescribe Mydocalm.

Mydocalm is a centrally acting muscle relaxant produced by the pharmaceutical concern Gedeon Richter in Hungary.

The main active ingredient of the drug is tolperizole. Its pharmaceutical activity is aimed at relaxing the skeletal muscles. Tolperizol does not have a depressant effect on the peripheral parts of the nervous system.

The main properties of the drug Mydocalm, which explain its effectiveness in treatment:

• local anesthetic action;
• blocking of spinal reflexes;
• increased peripheral blood flow;
• moderate antispasmodic, adrenoblocking action.

One of the indications for the use of the drug Mydocalm is osteochondrosis. Everywhere, doctors prescribe this medication for patients with its symptoms. At the same time, a person has doubts about the effectiveness of using Mydocalm, because there are different types diseases, and the drug is always recommended alone.

In order to dispel your doubts and understand that with the defeat of any parts of the spine, you can drink medicine, you need to know the principle of its action.

The medicine has the following properties:

1. antispasmodic (relaxes muscle tissue during its spasm);
2. anesthetic (does not act directly on pain, but eliminates it through relaxation);
3. vasodilating (normalizes blood flow);
4. sedative (has a calming effect);
5. lymphatic drainage (eliminates stagnation in the lymphoid tissue).

With all this, Mydocalm does not affect the functioning of the central nervous system, does not slow down the speed of impulses and does not cause drowsiness. The use of the drug is recommended for all patients with pain in the spine of any localization.

In the treatment of osteochondrosis of the spine with Mydocalm, the effect is achieved due to the effect on the smooth muscles of the skeleton. The drug relaxes the pathologically shrinking tissue, restores its original state. Due to this, blood flow is normalized, pinching of the roots, nerve endings and blood vessels is eliminated.

In order to carry out effective treatment of osteochondrosis, Mydocalm may require quite a lot. For a course of 10 days, exactly one package is enough. Tablets are available in a volume of 50 and 150 mg of active ingredient. This condition is provided for ease of use.

Considering that each pack costs about 400 rubles, for monthly therapy of osteochondrosis, you will have to purchase Mydocalm in the amount of 1200 rubles. Injections are more expensive. Each ampoule of Mydocalm costs about 100 rubles.

Often, the treatment of osteochondrosis begins with injections, and after a while they switch to tablets. How to take Mydocalm in this case and after how much to change the method of administering the medicine is determined by the doctor.

The results of treatment of osteochondrosis with Mydocalm in combination with other methods and drugs are usually not long in coming. With proper use and impeccable adherence to the recommendations of a neurologist, relief of well-being comes quickly.

Already on the first day of taking Mydocalm, the symptoms of osteochondrosis (in particular, pain) become less noticeable. On the third day of therapy, the maximum effect is achieved. It can be used to evaluate the effectiveness of the use of tablets and the need to increase their dosage.

When Mydocalm is prescribed by a doctor, a person with osteochondrosis should learn in detail about the treatment regimen:

1. how to take Mydocalm;
2. how many times a day to drink and how many tablets to take at a time;
3. whether to use injections instead of pills;
4. after what time it is possible to cancel the medicine or reduce its dosage.

Osteochondrosis cervical, which is diagnosed in patients most often, entails dangerous consequences. One of them is cerebral hypoxia. To prevent it, it is necessary to take Mydocalm exactly as much as the doctor prescribed.

It happens that patients feel relief from the symptoms of osteochondrosis and stop treatment on their own. At the same time, the spasm of muscle tissue persists, and the vessels continue to supply a small amount of oxygen to the brain.

As a result, complications develop, and patients talk about a strange set of circumstances: the treatment was carried out, but did not help.

The tool is available in the following forms:

Myokalm tablets have a round shape with a film coating. They contain different amounts of tolperisone and hydrochloride. Tablets with the number 50 on the surface contain 50 mg of active substances, and the engraving 150 indicates a triple dose.

Auxiliary substances are:

• stearic acid;
• titanium dioxide and silicon;
• lactose monohydrate
• microcrystalline cellulose
• citric acid monohydrate;
• dyes.

The injection solution is produced in tinted glass ampoules. The unit of medicine contains 100 g of tolperisone and 2.5 mg of lidocaine hydrochloride. The composition additionally uses red, yellow and black iron dioxide. One package contains 5 ampoules.

Mydocalm is available in injections and tablets.

The price of the tool is relatively high. There are substitutes (analogues) that have similar principles of action, but cost less.

Mydocalm is available in tablets and ampoules and is widely used in thirty countries, including Ukraine and Belarus. The drug is not an antibiotic, it belongs to the pharmacological group of muscle relaxants, the mechanism of action, excellent tolerance and the absence of a sedative effect have been proven in the course of complex clinical studies.

Mycolalm is a drug whose action is aimed at weakening muscle spasm, pain relief and improving the condition of the circulatory system. Mydocalm has three dosage forms: tablets, injection, ointment. The composition of the drug includes tolperisone, the main active ingredient reduces the sensitivity of nerve endings, relaxes striated muscles, increases peripheral blood flow, without affecting the hematopoietic system and kidney function.

The composition of Mydocalm includes two components tolperizole and lidocaine

Myorelaxant Mydocalm is available in solid tablet form, in injectable solution.

Mydocalm tablets are round, film-coated. The engraving on the tablets indicates the content of the active ingredient.

Dosage in solid tablet form:

1. tolperisone hydrochloride - 50 mg;
2. tolperisone hydrochloride 150 mg.

The injection form of Mydocalm is packaged in special darkened ampoules. One ampoule of Mydocalm contains 100 mg of the main active ingredient of tolperisone.

In addition to it, one ampoule of the muscle relaxant preparation additionally contains 2.5 mg of lidocaine hydrochloride.

This is a local anesthetic component of the drug. Components tolperizol and lidocaine enhance the therapeutic effect of each other.

Before you start treating osteochondrosis with Mydocalm, you need to make sure that there are no contraindications. Tablets and injections are prohibited if the patient is hypersensitive to the active substance, which is tolperisone.

It should be borne in mind that Mydocalm's solution for injection contains lidocaine. Many people, including those suffering from osteochondrosis, are allergic to it.

The doctor must take into account these comorbidities and prescribe alternative drugs for the treatment of osteochondrosis.

The drugs used for anesthesia provoke an increase in the concentration of the active substance Mydocalm in the patient's body. This condition must be taken into account if surgical treatment of osteochondrosis is planned.

Psychotropic drugs, which can also be used in the treatment of spinal pathologies, enhance the effectiveness of Mydocalm.

When using drugs based on niflumic acid, the symptoms of osteochondrosis become less noticeable, so drugs with anti-inflammatory and analgesic effects are also used for treatment. The interaction of these drugs with Mydocalm significantly increases their concentration in the body. Therefore, the dose of NSAIDs must be lowered.

The drug Mydocalm does not distort the effect of ethanol on the nervous system and brain, but you should not take the pill with alcohol. If you are planning a feast, then you need to take a dose of muscle relaxant no later than 2 hours before drinking alcohol.

The reverse rule also works: after drinking alcohol, you should not immediately take the next dose of Mydocalm. You need to take a break between them for several hours, and before using the pill, be sure to eat.

Usually, treatment with the muscle relaxant Mydocalm begins with a course of injections, and then the treatment is continued with a tablet form.

Taking into account the mechanism of action, the muscle relaxant drug Mydocalm is used and prescribed for many pathologies that are associated with muscle hypertonicity.

1. Reflex, compression complications of osteochondrosis: lumbago, radiculopathy, cervicalgia (pain in the collar zone), cervicobrachialgia (pain in the collar zone and arms).

2. Pathologies of the musculoskeletal system: spondylosis, spondyloarthrosis, lumbar, cervical syndrome, arthrosis of large joints, intervertebral hernia, lumbago. In traumatology and orthopedics, it is indicated in the rehabilitation treatment after fractures, operations on bones and joints.

3. Pathologies that are accompanied by pathological muscle hypertonicity against the background of brain disorders: pyramidal insufficiency, encephalitis, multiple sclerosis, consequences of acute cerebrovascular accident.

4. In pediatric practice for the treatment of Little's disease (spastic parases), muscular dystonia.

5. Pathologies with impaired soft tissue trophism: diabetic angiopathy, Raynaud's disease, autoimmune diseases, atherosclerosis.

6. The drug Mydocalm is prescribed for the treatment of pathologies caused by impaired innervation and blood circulation in the vessels: acrocyanosis, intermittent claudication.

With osteochondrosis of the cervical region, Mydocalm is recommended to drink in short courses. The average duration of muscle relaxant use is 7 to 14 days. If necessary, this period is extended up to a month.

Usually, patients during the treatment period receive a noticeable effect, relieving them of the symptoms of osteochondrosis and constant pain. Further therapy continues with the use of other techniques.

For individuals, the drug Mydocalm is effective, but when it is canceled, the signs of osteochondrosis return. Such patients are forced to take pills for a long time. Numerous experiments and studies have shown that Mydocalm is well tolerated and does not adversely affect the functioning of the body.

Therefore, patients with chronic osteochondrosis should not be afraid of long courses of treatment. You can use Mydocalm tablets for 7 years, periodically visiting a doctor and confirming the need for the drug.

If Mydocalm is prescribed with strict adherence to dosages, treatment with the drug is not accompanied by serious undesirable consequences.

But, if the patient complains of nausea, vomiting, abdominal discomfort, headaches and muscle weakness, the dosage of Mydocalm is reviewed and reduced.

If the injection form of Mydocalm is administered intravenously, rapid administration may be accompanied by dizziness, pre-syncope and severe hypotension.

The muscle relaxant drug Mydocalm is strictly contraindicated and prohibited for treatment in case of an allergic reaction in the form of skin itching, urticaria, erythema, angioedema.

Injectable solutions of the muscle relaxant Mydocalm is usually administered for 5-10 days

How to treat with a drug from the group of muscle relaxants, and what dosage form use, determined solely by the attending physician.

It will take into account the clinical picture, the severity of pain and spasm, age and constitutional data, concomitant diseases.

The Mydocalm treatment regimen also depends on the segment in which dystrophic changes associated with osteochondrosis have occurred: cervical, thoracic, lumbar, sacral.

If the injection of Mydocalm is indicated in the acute period, the regimen and dose for the treatment of osteochondrosis is as follows:

• intravenous administration - 100 mg once a day;
• intramuscular injection - 100 mg in the morning and evening.

After stopping the peak of spasm and pain in the acute period, the patient is prescribed Mydocalm tablets at the rate of 50 mg three times a day as maintenance therapy.

Osteochondrosis is a fairly common disease among patients over 40 years of age. The disease is accompanied by severe pain and other dangerous symptoms. During the course of the disease, changes are observed in the tissues of the vertebrae and intervertebral discs. Treatment of the disease is carried out with the help of drug therapy. Mydocalm is most often used for osteochondrosis, which is characterized by a high effect.

The drug belongs to the category of muscle relaxants, which allows it to be used for severe pain, which occurs as a result of pinched nerves in the spine during the course of osteochondrosis. The drug is very often used to treat an acute disease. Mydocalm for cervical osteochondrosis can be used in the form of injections or tablets.

The drug has a central effect. It affects the departments of the central nervous system. With the help of the drug, muscle tone is stimulated. Mydocalm is not used as an independent remedy for the treatment of osteochondrosis. It is a highly effective addition to the standard treatment regimen that uses non-steroidal drugs.

Important! After the release of Mydocalm, various studies were carried out, during which not only the effectiveness, but also the safety of the drug was proved. During its administration, soreness and muscle spasm are significantly reduced, which has a beneficial effect on the patient's condition.

The use of Mydocalm in osteochondrosis is carried out very often due to its unique composition. The release of the drug can be in the form of tablets or injections. Tablets of the drug preparation are characterized by a rounded shape and a film shell. Tablets may be engraved with "50" or "150".

These figures indicate the amount of the main component in one tablet, which is calculated in milligrams. Also, this form of the drug consists of additional components, which enhance the effect of the main component. One package of the drug consists of ten tablets.

Also, the release of Mydocalm can be made in the form of injections. Darkened ampoules are used for packaging the drug. The drug consists of lidocaine hydrochloride, tolperisone, black, red and yellow iron oxide. One package of the drug consists of five ampoules.

With the help of Mydocalm, neurological syndromes are cured, in which pain appears, trophism is disturbed and muscle tone increases. Due to the universal active substance, the drug is characterized by the presence of a membrane-stabilizing and anesthetic effect. That is why injections are often prescribed for osteochondrosis Mydocalm. At the initial stage of the course of the disease, the patient can take pills.

Attention! With the help of the drug, an indirect analgesic effect is carried out. While taking the drug, lymphatic outflow and blood circulation improve, which positively affects the effectiveness of treatment. During the reception of Mydocalm, muscle tension is eliminated.

Many patients ask about Mydocalm. Treatment of osteochondrosis with its use is carried out as simply as possible. This is due to the fact that the drug has a positive effect not only on the treatment of the disease, but also on general state patient.

The most commonly used Mydocalm injections for cervical osteochondrosis. Despite this, with the help of this drug, it is possible to treat thoracic and lumbar osteochondrosis. If the patient has a reflex or compression syndrome, then this requires the use of a drug. With its help, muscle rigidity is eliminated.

Most often, Mydocalm is used for osteochondrosis. Due to the high effect of the drug, it is used to treat:

• lumbar syndromes;
• spondylosis;
• arthrosis of large vessels;
• cervical syndromes;
• spondylarthrosis.

The drug is quite effective during the treatment of cerebral palsy. Also an indication for the use of the drug are encephalopathies, as a result of which the patient has muscular dystonia.

If the patient's muscle tone increases at a pathological level and at the same time muscle spasms are observed resulting from such neurological diseases as multiple sclerosis, myelopathy, encephalomyelitis, etc., then he needs to take Mydocalm. The drug is used in the postoperative period to eliminate the manifestations of osteochondrosis.

Despite high efficiency medication, it is characterized by the presence of certain contraindications:

1. If a patient is diagnosed with hypersensitivity to tolperisone, then taking Mydocalm is strictly forbidden to him.
2. Doctors do not recommend using the drug if a person has allergic reactions to lidocaine.
3. Treatment of children with a drug is carried out only under the strict supervision of a doctor.
4. Children under the age of one year are not recommended to take the drug.

Mydocalm, the course of treatment for osteochondrosis depends on many factors. This medicine is a highly effective medical product. With its use, you can get rid of various manifestations of the disease and stabilize the patient's condition.

Many patients ask how to take Mydocalm for osteochondrosis? Features of taking a medication directly depend on such factors as the clinical picture and the severity of the disease, the age of the patient, concomitant diseases. The treatment regimen for the disease also depends on which part of the spine was affected by osteochondrosis: cervical, lumbar or thoracic.

Adult patients are most commonly prescribed tablets of 50 milligrams. In patients with this, the question arises, how much to drink Mydocalm with osteochondrosis? The drug is taken three times a day. If the patient has severe spasms or a complex course of the disease is diagnosed, then the dosage of the drug can be increased three times. That is, patients need to take the drug in tablets of 150 milligrams three times a day. Tablets should be taken after meals.

With the help of Mydocalm, children can be treated. They need to take the drug three times a day. A single dose of the drug is 50 milligrams. In most cases, a special scheme is used to treat children. If the age of the child is from one to six years, then 5 milligrams of Mydocalm is relied on for one kilogram of weight, and if from 7 to 14 years, then from 2 to 4 milligrams per kilogram.

Important! Very often, children have difficulty swallowing a tablet. In this case, it must first be ground into powder.

After taking the drug inside, patients feel the effect of exposure after 40 minutes. Some patients are wondering how much to take Mydocalm for osteochondrosis? On average, the course of drug treatment lasts ten days.

The introduction of Mydocalm in the form of intramuscular injections is carried out twice a day. A single dose of the drug is 100 milligrams per day. In some cases, patients are prescribed intravenous injections. No more than one hundred milligrams of the drug per day is injected into the patient's vein.

With the correct use of Mydocalm, you can get rid of the manifestations of osteochondrosis as quickly as possible. The dosage of the drug should be made by a doctor after assessing the patient's condition.

If the patient has contraindications, the Mydocalm substitute is used for osteochondrosis, the prices and analogues of which can be varied. Most often, the drug is replaced by Miolgin, the main component of which is analgin, which provides it with an analgesic property.

An analogue of the drug is Tolperisone, which eliminates increased muscle tone. Instead of Mydocalm, Sirdalud can be used, which relieves painful muscle spasms. Analogues of Mydocalm are produced in the form of tablets and injections, which provides convenience during the treatment of patients.

Mydocalm is effective drug, which is widely used to treat changes in the cartilage of the joints of the spine. Thanks to the two forms of drug release, it is possible to provide maximum efficiency treatment of the disease. With osteochondrosis, the dose of the drug is prescribed by the doctor, depending on the individual characteristics of the patient and the course of the disease.

The tool is popular because it practically does not cause side effects, it has proven itself well among other similar muscle relaxants. If the treatment of osteochondrosis with Mydocalm is not possible, the medicine can be replaced with analogues. With chondrosis, such remedies are used;

You can replace the medicine with Baklosan.

In the treatment of ailments, it must be remembered that the exact dosage and duration of the course of administration is determined only by the doctor. You can not self-medicate, because you can cause even more harm to health. To get rid of osteochondrosis, an integrated approach to treatment is needed, and pharmacology is one of the methods. Massage, warming up and moderate physical activity are also needed.

In the pharmaceutical market, an injectable analogue medicinal product a muscle relaxant for an identical active substance is presented in the form of Tolperil.

The international and chemical name of the drug: TOLPERIL-ZDOROVYE, is produced by the pharmaceutical company "Health", Ukraine.

The amount of the active ingredient of tolperil hydrochloride, as well as lidocaine hydrochloride per ampoule, is identical to the muscle relaxant Mydocalm - 100 mg.

Drug name Price Purchase Pharmacy

Mydocalm
ampoules 1ml 5 pcs from 476 rubles. Buy Mydocalm
ampoules 1ml 5 pcs from 499 rub. Buy Mydocalm
tablets 150mg 30 pcs from 386 rubles. Buy Mydocalm
tablets 150mg 30 pcs from 420 rubles. Buy Mydocalm solution for injections 1 ml n5 amp from 360 rubles. Buy

Polina, 42 years old: Was treated for back pain. The doctor prescribed Mydocalm in injections. The first time the drug was administered intravenously, there was a terrible dizziness with a feeling of heat. AND ammonia gave a sniff, and the window was opened for fresh air. All this did not pass for almost half an hour. The second time I asked the nurse to administer the drug even more slowly, it was easier, I drank hot sweet tea before the injection.

Nina, 37 years old: Mydocalm was prescribed to me together with Diclofenac, when cervical osteochondrosis became very aggravated. Yes, indeed, the pain after taking the drugs gradually disappeared, she began to sleep well at night, she could move normally and turn her neck. The headaches also disappeared, but by the end of the drug treatment, muscle weakness appeared and the head began to spin.

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Mydocalm (active substance - tolperisone) refers to the central muscle relaxants (means that promote muscle relaxation). The mechanism of action of this drug has not been completely unraveled, which absolutely does not prevent its successful use in such pathological conditions as increased tone and muscle spasms. It has a membrane-stabilizing and local analgesic effect, reduces the sensitivity to pain of peripheral nerves, prevents the transmission of impulses along afferent (sensitive) and motor neurons, which, in turn, blocks mono- and polysynaptic reflexes of the spinal cord. Another possible, but not established for certain, property of mydocalm is the ability to prevent the release of biologically active substances - mediators due to inhibition of the entry of calcium ions into presynaptic nerve endings. In the spinal cord, mydocalm puts up a barrier to the spread of excitation along the reticulospinal pathway. Reduces the activity of a certain part of the brain responsible for muscle contractions - the caudal part of the reticular formation. This whole kaleidoscope of pharmacologically significant "technical and tactical characteristics" of mydocalm allows you to reduce pathologically high muscle tone, reduce their rigidity (stiffness, inelasticity) and susceptibility to spasms, facilitate functional and motor activity, while dulling pain.

The drug can also be prescribed to elderly patients, it is fairly well tolerated, does not have a toxic effect on the cardiovascular system, does not have a sedative effect and does not impair mental performance and other higher brain functions.

Mydocalm is available in tablets and ampoules (in the latter case, the designation "Richter" is added to the name of the drug). In the instructions for it, a strong recommendation is given to use this drug purely as directed by a doctor. Actually, it is unlikely to work out differently, because. Mydocalm is dispensed from pharmacies only by prescription. Tablets should be taken after meals, they should be washed down with a small amount of liquid, optimally - water. The standard initial dose for adults and adolescents over 14 years old is 50 mg, subject to 2-3 times daily intake, subsequently it is allowed to increase the dose of the drug to 150 mg with exactly the same frequency of administration. For younger age categories, the dose is calculated depending on body weight: 2-4 mg per 1 kg with a three-time daily intake (patients 7-14 years old) and 5 mg per 1 kg per day (patients 3-6 years old). With the injection method of administering the drug, a single dose is 1 ml of a solution administered twice a day (intramuscularly) or 1 time per day (intravenously).

Pharmacology

Muscle relaxant of central action. The mechanism of action has not been fully elucidated. It has a membrane-stabilizing, local anesthetic effect, inhibits the conduction of impulses in primary afferent fibers and motor neurons, which leads to blocking of spinal mono- and polysynaptic reflexes. It also probably secondarily inhibits the release of mediators by inhibiting the entry of Ca 2+ into the synapses. In the brain stem, it eliminates the facilitation of the conduction of excitation along the reticulospinal pathway. Enhances peripheral blood flow, regardless of the influence of the central nervous system. In the development of this effect, the weak antispasmodic and adrenoblocking effect of tolperisone plays a role.

Pharmacokinetics

Suction

After oral administration, tolperisone is well absorbed from the gastrointestinal tract. C max is reached in 0.5-1 h. Bioavailability is about 20%.

Metabolism and excretion

Tolperisone is metabolized in the liver and kidneys. The pharmacological activity of the metabolites is unknown. Excreted in the urine as metabolites (more than 99%).

Release form

Tablets, film-coated white or almost white, round, biconvex, engraved "50" on one side, with a slight characteristic odor; on a break of white or almost white color.

Excipients: citric acid monohydrate - 0.73 mg, colloidal silicon dioxide - 0.8 mg, stearic acid - 1.7 mg, talc - 4.5 mg, microcrystalline cellulose - 14 mg, corn starch - 29.77 mg, lactose monohydrate - 48.5 mg.

The composition of the film shell: colloidal silicon dioxide - 0.045 mg, titanium dioxide (E171) - 0.244 mg, lactose monohydrate - 0.392 mg, macrogol 6000 - 0.392 mg, hypromellose - 3.927 mg.

10 pieces. - blisters (3) - packs of cardboard.

Dosage

Tablets are taken orally, after meals, without chewing, with a small amount of water.

Adults and children from 14 years of age are prescribed at the beginning of treatment 50 mg 2-3 times / day, gradually increasing the dose to 150 mg / day 2-3 times / day.

For children aged 3 to 6 years, Mydocalm ® is prescribed in a daily dose of 5 mg / kg (in 3 divided doses during the day); at the age of 7-14 years - at a daily dose of 2-4 mg / kg (in 3 doses during the day).

Overdose

Data on an overdose of Mydocalm ® have not been reported.

There is no specific antidote. In case of overdose, gastric lavage and symptomatic therapy are recommended.

Interaction

Data on the interaction limiting the use of the drug Mydocalm ® is not available.

Although tolperisone has an effect on the central nervous system, the drug does not cause a sedative effect, so it can be used in combination with sedatives, hypnotics and preparations containing ethanol.

Does not affect the effect of ethanol on the central nervous system.

With the simultaneous use of Mydocalm ® enhances the effect of niflumic acid, therefore, if necessary, the use of this combination may require a dose reduction of niflumic acid.

Means for general anesthesia, peripheral muscle relaxants, psychotropic drugs, clonidine enhance the effect of tolperisone.

Side effects

From the side of the central and peripheral nervous system: muscle weakness, headache.

From the side of the cardiovascular system: arterial hypotension.

From the digestive system: nausea, vomiting, discomfort in the abdomen.

Allergic reactions: rarely - pruritus, erythema, urticaria, angioedema, anaphylactic shock, bronchospasm.

When the dose is reduced, adverse reactions usually disappear.

Indications

• treatment of pathologically increased tone and spasms of striated muscles resulting from organic diseases of the central nervous system (damage to the pyramidal tract, multiple sclerosis, cerebral stroke, myelopathy, encephalomyelitis);
• treatment of increased tone and muscle spasms, muscle contractures accompanying diseases of the organs of movement (for example, spondylosis, spondyloarthrosis, cervical and lumbar syndromes, arthrosis of large joints);
• rehabilitation treatment after orthopedic and traumatological operations;
• as part of combination therapy for obliterating vascular diseases (arteriosclerosis obliterans, diabetic angiopathy, thromboangiitis obliterans, Raynaud's disease, diffuse scleroderma);
• as part of the combination therapy of diseases arising from disorders of vascular innervation (acrocyanosis, intermittent angioedema dysbasia);
• Little's disease (infantile cerebral palsy) and other encephalopathies accompanied by muscular dystonia.