How to live with multiple sclerosis? Multiple sclerosis - non-drug treatments and diet. consequences and complications. Prevention of the disease and prognosis Tattoo with MS disease is possible or not

At carbon nanoparticles, tattooed, can selectively suppress the activity of T-lymphocytes and reduce the symptoms of autoimmune diseases.

This is evidenced by data from a study by American scientists published in the journal Scientific Reports. N+1 .

Researchers suggest to introduce nanoparticles preferably under the skin, which leads to its temporary staining, reminiscent of a tattoo.

Autoimmune diseases are a group of diseases with diverse manifestations (such as rheumatoid arthritis, multiple sclerosis, and many others) that have a common mechanism of development: for some reason, the immune system perceives the body's own tissues as foreign and attacks them, causing chronic inflammation.

In most autoimmune diseases, the key role is played by the pathological activation of T-lymphocytes, which damage cells by synthesizing reactive oxygen species.

Functionalized carbon nanomaterials, such as fullerenes or nanotubes, effectively neutralize reactive oxygen species, significantly surpassing natural antioxidants in this. Researchers at Rice University and Baylor College of Medicine have used hydrophilic carbon nanoclusters functionalized with polyethylene glycol (PEG-HCC) in their work. Such nanostructures have a powerful antioxidant effect and are non-toxic to cells. During the experiment, scientists injected PEG-HCC under the skin of rats and observed the behavior of nanoclusters in the body using antibodies to polyethylene glycol.

It turned out that the nanodrug is selectively absorbed by T-lymphocytes in the spleen, but not by other immune cells (macrophages, neutrophils, B-lymphocytes, and others). It also does not affect T-lymphocytes in the thymus, that is, it does not affect the process of their maturation.

Subcutaneous administration of the drug resulted in its slow release and, as a result, a longer and more uniform effect compared to intravenous injection. Already after the first injection, there was a decrease in the intensity of inflammation, and subcutaneous administration of the drug every three days significantly reduced the clinical and histological manifestations of encephalomyelitis.

Thus, PEG-HCC has prospects for use in autoimmune diseases, however, for its implementation in medical practice Numerous preclinical and clinical trials are needed. The scientists note that because the drug causes temporary skin staining, it can be injected using microneedles that are patterned so that the injection site resembles a temporary tattoo. This approach can improve the psychological state of patients and reduce the discomfort of drug administration.

Multiple sclerosis is a chronic non-communicable autoimmune disease that has nothing to do with what people most often mean when they mention "sclerosis". The reasons why a previously healthy organism begins to destroy its own cells - the myelin sheath of nerve fibers - in the brain and spinal cord and on peripheral nerve endings have not yet been clarified, but it is believed that lifestyle and heredity are of great importance in the development of the disease. sick.

So smoking and multiple sclerosis are closely related: according to American scientists, smoking can provoke the onset of this serious illness, due to which a person loses the ability to control his body. Today, multiple sclerosis is a not so rare disease that affects people, mainly young age- 15-40 years old, many of whom are smokers. They do not want to change their habitual way of life and give up their bad habits, but with some diseases, it is necessary to do this.

Smoking and multiple sclerosis

Smoking provokes not only the development of diseases of the respiratory tract and the cardiovascular system, studies conducted by foreign scientists prove that inhalation of cigarette smoke containing carcinogens has an extremely negative effect on human immunity, increasing the risk of developing multiple sclerosis by 2 times. A relationship was also noted between the age at which the subject began to smoke and the risk of multiple sclerosis.

As a result of the study, it was proved that those who started smoking before the age of 17 and continued until the time of the study had a 2.7 times higher risk of developing autoimmune diseases, in particular multiple sclerosis.

This dependence on age is explained by the effect of tobacco smoke on human DNA, especially the areas responsible for the body's immune response, in adolescence the immune system is not fully formed and with regular smoking natural defense human is imperfect, and therefore prone to autoimmune disease.

But smoking is harmful not only as a factor provoking the risk of developing sclerosis, smoking with a developed disease is even more dangerous - nicotine easily penetrates the blood-brain barrier and causes constant irritation of the nerve cells of the central and peripheral nervous system, greatly complicating and accelerating the course of the disease. And vasoconstriction and the accumulation of carcinogens in soft tissues further exacerbate the situation.

Multiple sclerosis - causes and symptoms of the disease

Like other autoimmune diseases, the exact causes of the development of multiple sclerosis are still not known, it is believed that the disease occurs as a result of exposure to the body of a complex of adverse factors - from poor environmental conditions to malnutrition and constant stress. As a result, an autoimmune process develops, in which the immune system begins to destroy its own cells - the myelin sheath of nerve fibers responsible for the conduction of nerve signals and the nutrition of nerve cells.

Lesions occur at different levels of the nervous system, without any logic - hence the name of the disease: "multiple sclerosis". Nerve fibers lose their protective sheath and are gradually replaced connective tissue ceasing to perform its functions.

The symptoms and course of the disease depend on which departments are affected and how fast the sclerosis of nerve fibers spreads. On early stages disease, the disease is almost asymptomatic, the patient may experience minor deviations in behavior, problems with performing certain actions, but all this is compensated by healthy nerve fibers that take on the functions of the affected.

But, as the zones of sclerosis spread, the symptoms increase - the main signs of the lesion depend on the location of the sclerotic areas - these can be problems with memory, speech, thinking, impaired coordination of movement, a sharp and unexpected decrease in vision or hearing. A person gradually loses the ability to control his body and his mind.

Is early diagnosis the key to successful treatment?

Unfortunately, so far effective treatment multiple sclerosis does not exist, only maintenance therapy has been developed, which should prevent the further development of the disease. Therefore, the stage of the disease at which treatment will be started is of great importance. Modern hormonal preparations, interferons and amino acid analogues can change the course of the disease and, if not stop, then significantly slow it down, but for this the disease must be diagnosed in time.

The impact of lifestyle on the course and treatment of multiple sclerosis

Autoimmune diseases are the strongest blow to the human immune system, a patient with multiple sclerosis is defenseless against other viral and infectious diseases. Therefore, a healthy lifestyle and the rejection of bad habits play a huge role in the treatment of multiple sclerosis.

Smoking and multiple sclerosis can negate all the efforts of doctors and the patient to treat the disease, cigarette smoke will become a constant irritant for the nervous system, and vasospasm and others harmful effects smoking will not allow medicinal substances to fully affect the affected areas.

Smoking is not only lung cancer and vascular disease, today cigarette smoke can lead to multiple sclerosis, and the treatment for this disease has not yet been invented.

WANT TO QUIT SMOKING?

Then join us for a marathon to give up cigarettes.
Not just quit smoking, not break loose.

Tattoo: contraindications for the procedure

Tattooing is the best assistant for any woman: it favorably emphasizes natural beauty, simplifies daily preparations and, in general, changes life for the better. However, in some situations it is not recommended to carry out the procedure or it is required to wait some time for the session, as a preliminary consultation with a doctor and special preparation for the tattoo procedure may be necessary. The reason for this is relative, and sometimes absolute contraindications for applying permanent makeup to some clients.

Absolute contraindications for tattooing

Due to the likelihood of side effects and complications, it is not recommended to get a tattoo in the presence of one of the following diseases:

• poor clotting and any blood diseases;
• insulin-dependent form of diabetes mellitus;
• acute inflammatory diseases;
• severe form of any somatic disease;
• epilepsy;
• bronchial asthma;
• oncological diseases;
• mental disorders;
• formations of unknown etiology;
• tendency to keloid scars;
• birthmarks in the intended tattoo area.

Note: however, in some cases, even in the presence of one of the above diseases, the application of permanent makeup is still possible, for this you need to consult with your doctor and get his permission for such a procedure.

Relative contraindications for tattooing

In the presence of any of the relative contraindications (described below), it is recommended to undergo preventive training with appropriate medicines to get the best result from the tattoo procedure.

Contraindications requiring preliminary preparation to the procedure:

• allergies (permanent makeup uses hypoallergenic pigments, but it is important to consult a doctor if there are any allergic reactions to anesthetic creams and other drugs used during a tattoo session);
• high blood pressure (people with hypertension should have their blood pressure measured before getting a tattoo and take a blood pressure medication if necessary)
• inflamed skin in the area of ​​​​the future tattoo (in the presence of purulent foci, you must first visit a dermatologist);
• herpes in the acute stage (before the tattoo procedure, you should definitely drink a course of an antiviral drug).

Important: It should be borne in mind that for people who suffer from herpetic rashes on the lips, permanent makeup is simply indispensable, because thanks to it:

a) there is no need to constantly use gloss, lipstick and other decorative cosmetics, which is one of the main causes of lip irritation, and sometimes their infection;

b) the border of the lips is compacted, which prevents the frequent rash of herpes.

tendency to inflammatory diseases mucous membranes of the eyes (for example, conjunctivitis).

Note: for applying permanent makeup in the presence of such a relative contraindication, a small preliminary check is recommended:

In case of an allergic nature of the disease, a skin test is required - apply a small amount of ointment and pigment to the elbow bend, which will be used during the procedure;

With the infectious nature of the disease, it is necessary to consult an ophthalmologist who will advise special drops to normalize the condition of the mucous membrane of the eyes.

Note: for people suffering from conjunctivitis, tattooing is not only possible, but really necessary, since the procedure eliminates the need to use decorative cosmetics, which is a serious irritant for the mucous membrane of the eyes, to the maximum. Consequently, after the session, the negative external influence decreases, and the disease subsides.

You will also have to wait a little with applying a tattoo when:

• pregnancy and lactation (this procedure is completely contraindicated in the first trimester of pregnancy. As for the second and third trimesters and the period of breastfeeding, at this time, permanent makeup is possible, but only if the procedure is easily tolerated (i.e. without the use of anesthetics) and consent obtained from the supervising physician);
• menstruation ( best time for tattooing - the middle of the cycle);
• weakening of the immune system (during the rehabilitation period after surgery or a serious illness);
• elevated temperature;
• taking strong antibiotics, dietary supplements, etc.;
• any degree of intoxication.

From the moment a person learns about his diagnosis, some time must pass so that he can rethink everything in life and accept this disease.

Now it is very important for him to find out what is possible with MS and what is not, because the condition of a person with this diagnosis directly depends on this.

The disease has different forms course and can often recur, but in order to avoid exacerbations as much as possible, it is necessary to clearly understand what can provoke such conditions and avoid adverse factors.

Effect of high cholesterol on atherosclerosis

If cholesterol begins to rise, then this can carry many threats to the body. First, consider what it is.

Cholesterol is a type of fat called a lipid. It is used in the body for various purposes.

One of them is the formation of new cells. Cholesterol is produced by the liver. But in addition, it can enter the body with food.

The body needs a certain amount of it. With an excess of cholesterol begins to be deposited on the walls of the arteries.

Cholesterol plaques grow in size, which prevents blood from moving through the vessels. For this reason, all tissues and organs lack nutrients.

Arteries harden and become less elastic. This leads to clogged arteries and atherosclerosis.

The reasons that the level of cholesterol in the body may increase are:

• hereditary diseases;
• diseases of the kidneys, liver and pancreas;
• diabetes;
• hypertension;
• hypothyroidism;
• pregnancy;
• alcohol abuse;
• smoking, both active and passive;
• obesity;
• acquired chronic diseases;
• taking certain medications.

Cholesterol and smoking are linked bad habit increases the level of this lipid in the body. And this can lead to the early development of atherosclerosis.

Cigarette smoking and atherosclerosis of arterial vessels should by no means be associated. For people suffering from this disease, a bad habit can cause irreparable harm.

Many studies have confirmed that people who smoke for a long time have multiple sclerosis in a very severe form, so after establishing a diagnosis, doctors recommend quitting smoking.

Heavy smokers who have this disease face a severe deterioration in the condition. In patients leading a healthy lifestyle, the disease proceeds in fits and starts with short-term exacerbations, after which the condition improves markedly.

This variant of events is very rare in smokers. There is a high probability of the transition of the state into a progressive one.

If you have symptoms of a disease, you should consult a doctor. After the diagnosis is established, it is urgent to abandon the bad habit.

Improvement of the nervous system will come after a couple of months of life without cigarette smoke.

Lifestyle with this diagnosis

For the most part, a person should continue to lead a normal lifestyle, excluding activities that are contraindicated. Of course, the disorders in the body that this disease causes do not always allow a person to do the same thing that he did before the disease, but this is not a reason to give up, you can always and should look for an alternative.

Important! The psycho-emotional state of the MS patient determines how he will feel.

What can not be done with this disease?

What do you need to pay attention to?

People diagnosed with MS should first pay attention to what they eat. Nutrition should be balanced, to a large extent, foods rich in unsaturated acids should be present. This is first of all:

1. nuts;
2. whole grain cereals;
3. vegetable oil.

Reference. Fresh vegetables and fruits should be consumed in sufficient quantities.

Foods rich in vitamins and beneficial trace elements will contribute to increased metabolism in cells. Ashton Embry and Roy Swank's diet has gained particular popularity.

Also, people diagnosed with MS should regularly exercise. It's about easy therapeutic gymnastics, and not about intensified and exhausting exercises, which, on the contrary, are contraindicated.

Drinking alcohol

Alcohol harms the health of a person with MS in the same way as a healthy person. It is hardly worth exposing yourself to an increase in MS symptoms (unsteadiness when walking, blurry or double vision) by abusing alcohol.

marijuana use

Later life in MS

Medications

With an exacerbation of MS, pulse therapy is often used, usually using Solumedrol. To change the course of multiple sclerosis long time PITRS drugs are injected, these include: Copaxone, Axoglatiran, etc.

Depending on the symptoms of the course of the disease, in each case, different kinds of drugs are used.

Important! The appointment of drugs is strictly qualified neuropathologist.