Metronidazole for thrush in women. Metronidazole in the treatment of thrush, instructions for use. How to use external dosage forms

Thrush is a disease of the reproductive system. Most often it occurs in females. To date, it is quite easily cured. The most popular remedy is Metronidazole for thrush. Its action is coordinated to remove fungi, which are the causative agents of thrush.

Thrush is often caused by a variety of fungal infections. That is, not they themselves, but those states with the help of which their growth is enhanced. From this we can conclude that the cause of thrush can be a variety of hormonal disorders that can occur during pregnancy or as a result of taking a variety of contraceptives. Companions of thrush are also pathologies of the thyroid gland or diabetes mellitus. Despite the cause of this disease, Metronidazole helps against thrush at a high quality level.

One of the main symptoms of thrush is a white (milky) discharge from the vagina. They are accompanied by itching and an unpleasant odor. If a woman had thrush during pregnancy, then this disease is transmitted to the child. In a child, the symptoms of this disease are a light plaque in the oral cavity. Men during thrush experience itching and a feeling of dryness. Also in the area of the glans penis and foreskin men have redness. In addition, men feel increased pain and burning after intercourse.

Treatment

The drug is available in the form of a gel, suppositories and tablets. Candles Metronidazole from thrush are quite effective for the treatment of diseases in women. It is easiest for men to use tablets or gel. It is an antiprotozoal, antibacterial agent, which is characterized by a wide spectrum of action. Treatment of thrush with Metronidazole is quite highly effective due to its high penetrating ability, tk. characterized high level influence on various types of bacteria.

How to take Metronidazole for thrush?

It is taken in combination with other drugs. This remedy alone will not be enough to completely get rid of the disease. Metronidazole tablets for thrush can be taken by women, men and children. The dosage of the drug depends on the degree of complexity of the disease and the individual characteristics of the patient. Metronidazole for candidiasis is taken in combination with douching and vaginal suppositories. Metronidazole for thrush in women, although it is a highly effective remedy, has its own side effects. Nausea, vomiting, or headache may occur after taking this drug. Thrush after metronidazole does not appear enough long time. The only condition is the need to monitor the hygiene of the genitals.

Now you no longer need to ask the question: "Can Metronidazole cure thrush?" Of course you can. Only before treatment it is necessary to consult a doctor. An experienced specialist will talk about the dosage of this medication, as well as prescribe concomitant drugs for the treatment of the disease.

The drug is a very highly effective drug against thrush. It's proven big amount patients who got rid of this Candida fungus with its help. It is prescribed to all patients, regardless of their gender and age.

Thrush is a disease that got its name from its main feature - intense white curdled discharge resulting from the inflammatory process of the vaginal mucosa. Provoke the inflammatory process yeast-like fungi of the genus Candida.

Symptoms of the disease do not always manifest themselves, but in the case of an increase in the intensity of reproduction of yeast fungi, candidiasis manifests itself quite clearly.

Establishing diagnosis
Forms of release and indications for use
Taking medication for various ailments of the genital area
Preparations in the form of suppositories containing a substance

Establishing diagnosis

Diagnosis and treatment of the disease is carried out by a specialist in the field of gynecology, a gynecologist. The main unpleasant signs of vaginal candidiasis are:

If a woman is concerned about only one of the listed signs, then we can talk about the erased course of vaginal candidiasis. And if a woman is not given due attention to the treatment of thrush, then she can become chronic and return to the patient at least four times a year.

Thrush that has become chronic is more difficult to cure, and it often leads to secondary diseases of the genital area.

The reasons leading to the occurrence of the disease are many:

The diagnosis of the disease and its treatment is carried out by a gynecologist, who must be contacted immediately, when the first signs of a developing disease appear. The specialist will conduct all the necessary studies and prescribe an adequate treatment strategy.

Therapeutic therapy of vaginal candidiasis is performed according to the basic principles:

Identify and eliminate the causes of the disease.
Normalize the metabolism in the body.
Restore the protective functions of the body.
Eliminate intestinal dysbiosis.
Normalize the acidity of the vaginal environment and its microflora.

After completing the course of treatment, the patient must undergo a second examination to exclude the latent course of the disease and establish the fact of recovery.

Forms of release and indications for use

In gynecology, Metronidazole is often prescribed to combat many diseases. The drug has a wide range of actions and is able to quickly improve the patient's condition. Since Metronidazole is an antimicrobial, antibacterial drug, it is used in combination with antifungal agents to treat thrush.

And in connection with his helplessness against certain types of fungi, before his appointment, it is necessary to carefully establish which pathogenic organism has become the causative agent of the disease.

Metronidazole is available in several forms:

Pills.
Cream.
Candles.
Solution.

The drug in the form of tablets is effective against the unpleasant manifestations of vaginal candidiasis. Tablets can also be taken by men against candidiasis, as well as a drug in the form of a gel.

It is more expedient for women to use the drug in the form of vaginal suppositories. The drug in the form of a solution in ampoules, used intravenously through droppers, is more often prescribed against lung infections, gangrene and organ infections. abdominal cavity.

Metronidazole can be prescribed if the patient is diagnosed with:

Taking medication for various ailments of the genital area

With bacterial vaginosis, the use of Metronidazole is the most optimal method of treatment. The recommended dose is 0.5 g orally in tablet form, twice a day. The course of taking Metronidazole for bacterial vaginosis is at least a week.

Despite the possible side effects of taking the drug and its absolute incompatibility with alcoholic beverages, bacterial vaginosis can be successfully treated and there is practically no risk of bacterial vaginosis moving into more complex forms and stages.

In addition to the use of tablets, bacterial candidiasis is treated with a gel. It is injected into the vagina at least twice a day. The course of treatment is five days.

It is worth noting that with vaginosis Metronidazole in the form of tablets is prescribed in the presence of related infectious diseases. In other cases, it is more expedient for women to carry out therapeutic therapy with vaginal suppositories.

In the case of an acute form of trichomoniasis, a loading dose of the drug (2 g) is prescribed at a time. In some cases, with trichomoniasis, the following treatment regimen can be prescribed: 0.25 g twice a day, a course of 10 days. Chronic trichomoniasis is treated according to the scheme: 0.5 g of the drug, three times a day, a course of 12 days.

If trichomoniasis is diagnosed in a woman in a state of pregnancy, and the risk of complications of the disease is high, then starting from the second trimester of pregnancy, Metronidazole, 2 g once, at bedtime, can be taken.

Complicated trichomoniasis, recurrent trichomoniasis, as well as in cases of carriage of trichomoniasis, the drug is prescribed as follows: 0.5 g three times a day, for at least 12 days. At the time of treatment of trichomoniasis with Metronidazole, it is necessary to completely abandon the use of alcoholic beverages.

For therapeutic therapy against Giardia, the dosage of a single dose is from 0.5 to 1.5 g, with a course of up to 5 days.

For patients diagnosed with gardnerellosis, Metronidazole is prescribed both topical application of the drug in the form of a gel and suppositories, and oral administration of tablets. The drug is used for gardnerellosis in the form of a gel or suppositories, mainly at night, by introducing suppositories or gel into the vagina, and in the case of an acute course of gardnerellosis, the drug is injected into the vagina several times a day, morning and evening.

In the form of tablets, a remedy for gardnerellosis is prescribed twice a day. Due to the ability of Metronidazole to destroy the DNA of anaerobic microorganisms, it is quite effective in this disease. The drug has a high permeability and accumulates not in the blood, but in the focus of accumulation of pathogens. The withdrawal of funds occurs through the kidneys.

Ureaplasmosis is also treatable with Metronidazole. The drug against ureaplasma is used mainly in the form of tablets. The method of using Metronidazole against ureaplasma differs from the treatment of other diseases. Drink a tablet exclusively during meals, washed down with a glass of milk. Taking the medicine on an empty stomach with water is strictly prohibited. It is also forbidden to break or crack the tablets. Side effects in the treatment of ureaplasma with Metronidazole:

When treating, it is important to consider that the simultaneous use of Metronidazole with alcoholic beverages leads to adverse effects.

Treatment of chlamydia is also carried out with Metronidazole, but in this case, parallel administration of amoxicillin is often prescribed. The fact is that chlamydia quickly adapt to Metronidazole, and the combined use of two drugs enhances the action of both drugs, eliminating the development of bacteria adaptation to Metronidazole, making therapeutic therapy against chlamydia more effective.

Side effects of metronidazole in the treatment of chlamydia:

If you find one of the above signs in yourself, it is recommended to immediately inform the specialist who prescribed the treatment.

Vaginal suppositories Metronidazole for thrush are prescribed only in combination with antifungal drugs, because. they are not effective against certain fungi that cause candidiasis. Candles have many contraindications for use, and, in case of hypersensitivity to the drug, the candles are replaced with a gel that is applied topically, on the external genital organs, to relieve the unpleasant symptoms of candidiasis.

Important! Metronidazole is contraindicated for the treatment of women during pregnancy and during breastfeeding!

Preparations in the form of suppositories containing a substance

Treatment of diseases of the genitourinary system is more appropriate to carry out locally, using vaginal suppositories.

The most popular preparations in the form of vaginal suppositories containing the antiseptic metronidazole are:

Metronidazole suppositories;
Metrovit;
Metrovagin.

Apply preparations in the form of vaginal suppositories once a day, mainly at night. The course of treatment is, on average, ten days. A specialist, a gynecologist, a course of treatment can be re-appointed no earlier than a month later.

Despite the local use of drugs, they are contraindicated during pregnancy and lactation. They also do not recommend their use in cases of blood and central nervous system diseases. An important condition for the treatment of these drugs is the complete rejection of the use of even the weakest alcoholic beverages.

Side effects in the treatment of drugs in the form of vaginal suppositories can occur from the genitourinary, digestive and nervous systems.

The effectiveness of treatment with drugs with metronidazole increases when they are used together with vaginal suppositories containing nystatin. Reception of these funds is prescribed in the first half of the woman's menstrual cycle, after critical days. At the time of therapeutic therapy, it is necessary to limit visits to pools, ponds and baths. It is also worth refusing to douche.

Conducting therapeutic therapy of diseases of the genital area, it is necessary to jointly examine and treat the patient's sexual partner.

How to take "Nystatin" with thrush

05/28/2015 // admin

"Nystatin": how to take the drug will guide the doctor. After all, it is possible to be treated with this drug only after the doctor prescribes it. But a person who cares about his health will always know Additional information medicine before trusting him with your recovery.

This drug has an antifungal effect on the body. Therefore, most often, it actively and quickly copes with yeast fungi. We hope that you are already aware that thrush appears against the background of favorable factors for fungi of the genus Candida, due to which yeast fungi begin to lead their active life and interfere with ours. Are these suppositories suitable for restoring microflora in women?

Details about the principle of operation

At the heart of the drug "Nystatin" (how to take, we'll talk a little later) is an element of antibiotic origin. That is, this active substance can enter the cell membranes of fungi and act on the bottom from the inside.

Fungi have their own immunity that protects them. But when the drug enters the membrane, it weakens the immune system, as a result, ions enter the cell, which lead to the death of Candida. In the worst case, the process of reproduction of fungi with the help of the drug will be slowed down, and in the best case, they will all be destroyed.

Important! "Nystatin" affects only fungi of the genus Candida, which cause thrush. They do not provide their negative impact on other microorganisms that can bring their benefits to the human body.

When to use Nystatin

Before moving on to the question of how to use Nystatin, you need to understand when it will help. Doctors of the unit prescribe this remedy, both in acute and chronic forms of candidiasis. The drug does not cause addiction, so fungi practically cannot become resistant to it. To use this drug, you will need to get a doctor's prescription.

About contraindications

First of all, the instructions indicate individual intolerance, including allergies. The use of Nystatin suppositories or other forms of this drug during pregnancy is also prohibited, as is the use of the drug during breastfeeding. For problems with the gastrointestinal tract, the medicine is used carefully.

Side effects

Manufacturers report availability side effects especially in the early stages of admission. Most often, itching and burning are manifested, redness, and a rash are possible. When taking pills, the patient may feel nausea and vomiting, often patients complain of pain in the abdomen.

To minimize side effects, necessary:

Use the medicine only on the advice of a doctor;
During treatment, do not drink alcoholic beverages;
Do not be treated simultaneously with the use of the drug "Clotrimazole". The latter significantly reduces the positive effect of the drug "Nystatin";
During critical days, the introduction of candles should be refrained from;
In the process of treatment, you should try not to enter into intimate relationships;
If the sexual partner is permanent, then treatment for thrush is carried out in pairs;

How to take Nystatin

The final regimen for a particular situation must be agreed with the doctor. But, there general recommendations on admission. It all depends on the form of the drug.

Vaginal (rectal) suppositories

Administered twice in the morning and evening. The full course of treatment is from 10 to 14 days. Candles can also be inserted rectally. In one package, as a rule, there are ten candles, the dosage is from 250 to 500 thousand units of active ingredients in each. What drugs to take to restore microflora after thrush?

Has a local effect. It must be applied to the lesions of the mucosa. Treatment lasts 10 days. One gram of ointment contains 100,000 units of active ingredients.

Pills

The scheme of admission will be individual. Tablets are sold in a dosage of 250-500 thousand units of the drug. They can be of different sizes.

Important! If the thrush is chronic, then you need to combine the ointment (or suppositories) with taking pills. The dosage may vary depending on how advanced the candidiasis is in a particular patient. Find out if there can be thrush after conception.

Taking the drug "Nystatin" with thrush

A doctor may prescribe any of the forms of this drug for candidiasis. As a rule, a local effect is most often prescribed, which means that candles or ointment are prescribed.

Before you insert a candle into the vagina, you will need to wash and wash your hands. Most often, a suppository dosage of 500 thousand units is prescribed, less often 250. We already wrote how to take Nystatin in the form of suppositories: enter in the morning and evening.

If the doctor has prescribed the use of Nystatin ointment, it is applied to the affected areas twice a day. Often the ointment is combined with suppositories for complex treatment. This is typical for chronic thrush.

If earlier "Nystatin" was used quite often for thrush, then recently doctors rarely prescribe this particular remedy. This is because the pharmacological industry offers many other antifungal drugs. But, if the doctor has prescribed a medicine, then it is important to discuss with him in advance how to take Nystatin in a particular situation.

Almost every woman at least once in her life faced with a fungal infection. For many, her unpleasant symptoms become a problem that comes back again and again.

In search of a cure, it is important not to get confused. Antifungal drugs are used to treat fungus. Metronidazole for thrush is prescribed for a combination of fungal and bacterial infection, when complex treatment is required.

Inflammation of the mucous membrane of the vagina and vulva caused by the Candida fungus. Candida can be part of the normal microflora of the intestines, skin, oral cavity, vagina. Symptoms appear when defenses are reduced and conditions are created for the reproduction of the fungus. A fungal infection is a signal of a general trouble in the body.

In the people, thrush is a synonym for any infectious diseases of the vagina and vulva with discharge, itching, burning, swelling and redness of the genitals.

It can be bacterial vaginosis, trichomoniasis, gonorrhea, ureaplasmosis, chlamydia, etc. Each of these infections requires specific treatment. Although their symptoms may be similar.

What contributes to the onset of symptoms?

Decreased immunity. During pregnancy, lactation, in newborns, in the elderly. Physiological immunodeficiency is observed. There are other reasons that lead to impaired immunity. Severe diseases of the liver, blood systems, oncological diseases, viral diseases (HIV), severe injuries and burns.
Violation of the microflora of the vagina, intestines. This can be caused by taking antibiotics.
Violation of the hormonal balance in the body. First of all, this applies to sex hormones - the use birth control pills. Diabetes, pathology of the thyroid gland.

itching and burning are unbearable. Aggravated at night, on contact with water and urine;
curdled discharge from the genital tract;
the vulva and vagina are edematous, red with microcracks. In the folds between the labia and on the walls of the vagina, a white curdled coating;
pain during intercourse due to microcracks and inflammation of the vagina;
violation general condition, depression, anxiety;
pain during urination and in the lower abdomen when the fungus spreads to the urethra, bladder, kidneys.

Who makes the diagnosis and how?

The diagnosis is made by a doctor after a laboratory examination. To do this, take a smear from the vagina and examine it under microscopes. In some cases, the doctor may prescribe a culture of flora on a nutrient medium. After obtaining the growth of colonies of the fungus, its sensitivity to drugs is determined.

Although a fungal infection is widespread, it is difficult to treat.

It is necessary to destroy the fungus, find and neutralize the cause that contributes to the development of a fungal infection. Restore the microflora of the vagina and intestines. This is what probiotics are for. As well as activate the body's defenses to fight and self-defense. Use vitamins, antioxidants, immunomodulators.

First of all, antifungal drugs are prescribed. They are also called antimycotic or fungicidal. This:

polyene antibiotics: nystatin, natamycin, amphoicin B;
azoles: itraconazole, butoconazole, miconazole, econazole, fluconazole;
pyridines: ciclopirox.

The insidiousness of the fungus is that it is often combined with a bacterial infection, in particular with bacterial vaginosis - the causative agent of gardnerella. In such cases, infections mask each other and are difficult to treat.

In such cases, combined preparations with an antifungal and antimicrobial component are used. In this case, metronidazole will be effective. Most often, suppositories or vaginal tablets with metronidazole are used and antifungal drugs:

metronidazole with miconazole. Trade names of drugs: gynocaps, klion D, metromicon, limenda, rumizol, neo-penotran;
metronidazole with clotrimazole and neomycin sulfate - clomesol;
metronidazole with fluconazole - vagisept.

Metronidazole - a brief description

Metronidazole has:

Released as:

oral tablets;
injection;
vaginal suppositories and tablets;
ointment;
cream;
gel.

Metronidazole is built into the respiratory chain of microorganisms and blocks this process. This leads to their death. Violates the formation of microbial DNA and causes its destruction.

It is excreted from the body by the kidneys, while the urine turns red-brown, and through the intestines. When taking the drug, there are false positive reactions to syphilis.

Who is afraid of metronidazole and when to take it?

Trichomonas;
Vaginal gardnerella;
Giardia;
Giardia;
Amoeba.

Anaerobic microorganisms live in the absence of oxygen. Many of them are opportunistic pathogens. They are part of the normal microflora of the intestines, vagina, skin, oral cavity.

With a decrease in protective forces, taking antibiotics cause diseases: dysbacteriosis, bacterial vaginosis:

Fusobacteria;
Bacterioids;
Provetel;
Villionels;
Clostridia;
Peptostreptococci;
Peptococci.

Metronidazole helps with:

trichomonas vaginitis, urethritis;
bacterial vaginosis;
inflammatory diseases of the uterus, fallopian tubes, ovaries;
after operations for the prevention of infectious complications, especially in gynecology;
bone infections;
soft tissue infections: bedsores, long-term non-healing wounds;
skin infections: acne vulgaris and rosacea, seborrheic dermatitis;
infections of the abdominal cavity (peritonitis, liver abscesses);
amoebic dysentery;
giardiasis;
pseudomembranous colitis after using antibiotics;
peptic ulcer of the stomach and duodenum, together with amoxicillin destroy Helicobacter pylori;
purulent-inflammatory diseases of the maxillofacial region;
lung abscesses, empyema, pneumonia, bacterial endocarditis;
to improve the sensitivity of the tumor to radiation therapy;
treatment of chronic alcoholism.

Metronidazole does not have a fungicidal effect, i.e. not effective against fungi.

On the contrary, when using the drug, beneficial bacteria die - representatives of the normal microflora, which can lead to a violation of the biocenosis of the vagina, intestines and the growth of fungi.

But, metronidazole is used as part of combined preparations along with antifungal drugs.

They are prescribed for a combination of bacterial and fungal infections.

Metronidazole destroys bacteria: gardnerella, Trichomonas, anaerobes, and a fungicidal preparation - a fungus.

When is metronidazole contraindicated?

With allergies and hypersensitivity.
With leukopenia. Metronidazole, which helps with bacterial infections, with long-term use can affect the hematopoietic system and cause a decrease in the number of neutrophils. The body becomes defenseless against infections.
With epilepsy and other diseases of the central nervous system.
With liver failure. Metronidazole is detoxified in the liver before being excreted from the body. If its work is disturbed, it accumulates in the body.
With renal failure. Carefully.
When lactating, you can not drink metronidazole. Metronidazole passes into breast milk. When using it and 2 days after the end of the breast do not feed.
In pregnancy up to 12 weeks, metronidazole is contraindicated. After 12 weeks, they are prescribed according to strict indications.

You can not take the drug with alcohol. Metronidazole causes symptoms similar to poisoning when combined with alcohol: nausea, abdominal cramps, vomiting, redness of the face, headache.

From the side of the central nervous system - headache, dizziness, confusion, insomnia, depression. This should be remembered when driving.

From the digestive system - diarrhea, nausea, vomiting, loss of appetite, constipation, intestinal colic, "metallic" taste in the mouth.

From the genitourinary system: cystitis, dysuria, urinary incontinence, polyuria.

On the part of the blood - leukopenia. Allergic reactions: skin rash, urticaria, skin flushing, fever, nasal congestion.

Local reactions:

when injected into a vein - thrombophlebitis;
peeling, hyperemia and burning of the skin;
when used near the eyes - lacrimation.

Metronidazole vaginal suppositories can cause itching and burning in the vagina, white, thick, mucous vaginal discharge with little or no odor, and frequent urination. Feeling irritation or burning of the penis in the sexual partner.

Often, urogenital candidiasis in women is associated, that is, with the addition or on the background of a bacterial infection, which is sometimes difficult to treat. An important point it remains the selection of an adequate and suitable one, therefore, this article will discuss how to take Metronidazole for thrush and when it is not recommended to do so.

Metronidazole is a drug that has not only an antimicrobial, but also a protozoal effect. At the same time, it has a bactericidal and antiulcer effect.

In medicine, the drug is used as a therapy for infectious diseases of the peritoneal cavity, the osteoarticular system. It is successfully used in the fight against gynecological pathologies, trichomoniasis and acne.

Release form: candles and tablets

Metronidazole for candidiasis is used only in its two dosage forms - in and. The latter are round in shape and greenish-yellow in color, with a bitter taste. Available in standard blister packs of 10 or 20 pieces. Dose of the active substance: the tablet may contain 500 and 250 mg. Auxiliary components are represented by starch, acetylacetic acid and steatite.

Candles have a rocket-like appearance and whitish-yellow color. One suppository may contain 500, 250 or 125 mg of the active substance. The cellular package contains 7 suppositories intended only for intravaginal administration.

Properties

Metronidazole has the following effects:

Antibacterial.
Antiulcer.
Antiprotozoal.

The mechanism of action is based on the biotransformation of the active substance and the restoration of its 5-nitro group under the influence of transport proteins of protozoa and bacteria. Reduced metronidazole affects the DNA of the pathogen cell, blocking the synthesis of nucleic acids in it. As a result, the destruction of pathogenic microorganisms.

The drug also has a bactericidal effect on obligate anaerobes. Metronidazole fights against mixed infections only as part of complex therapy with antibacterial agents. In the treatment of peptic ulcer, the drug also comes with amoxicillin, which prevents the development of H. Pylori resistance to metronidazole. Similar to disulfiram, it promotes the development of sensitization to ethylene, stimulates regeneration processes.

Dosages

For the treatment of acute or metronidazole tablets, 250 mg is prescribed twice a day for 10 days. Non-specific vaginitis involves the use of 500 mg tablets, which are drunk once a day or divided into 2 times, also for at least 10 days.

Candles Metronidazole with thrush is introduced into the vagina 1 piece (500 mg) in the morning and at night before bedtime. The course of treatment should not exceed 5-10 days. Or you can use suppositories once at a dose of 2 grams.

Side effects and contraindications

Instructions for use Metronidazole for thrush states that the drug is contraindicated in:

The presence of individual hypersensitivity to the components of the drug.
Any stage of liver failure.
CNS lesions of an organic nature (tumors, degenerative diseases, epilepsy, etc.).
early period.
Decreased white blood cell count (leukopenia), even in history.

While taking the tablets, patients may develop some adverse reactions. Most often, these are dyspeptic symptoms (nausea, abdominal pain, vomiting, thinning and frequent stools), weakness, headaches, insomnia, dizziness. In some cases, seizures, hallucinations and confusion may occur. Also, a woman may complain about the joints and burning sensation in the area of the external opening of the urethra. Somewhat less common are allergic reactions to the drug and symptoms of dysuria.

How to use?

If metronidazole tablets for thrush are prescribed as a treatment, then they should be taken at the indicated dosage during or immediately after a meal. Do not chew, but drink plenty of clean water. It is desirable that the use of the drug is carried out at the same time of day.

Before you start administering Metronidazole vaginal suppositories for thrush in women, it is necessary to have an evening intimate toilet of the external genital organs and wash your hands thoroughly. Having taken a comfortable position (lying on your back with legs bent and spread apart), the candle is inserted into the vaginal cavity with slow and gentle movements as deep as possible. In order to prevent the molten substance from flowing onto the underwear, it is advisable to first put a pad on it. After the introduction, the woman should lie down for at least 30 minutes.

Can thrush be cured with metronidazole?

Many patients ask themselves: is it possible to cure thrush with suppositories or Metronidazole tablets? In fact, this is not a specific antifungal drug, but an effective combined remedy that is prescribed both in isolation (for the treatment of bacterial or protozoal infections) and as part of complex therapy.

Its appointment for candidiasis is justified if there is an infection associated with bacteria, that is, when thrush occurs against the background of nonspecific or specific colpitis.

Thrush recurrence after treatment with Metronidazole

Recurrent thrush after Metronidazole is possible if the therapy did not include systemic and local action, which should be selected taking into account the sensitivity of the pathogen. Candidiasis is caused by yeast-like fungi, which are completely unaffected by the active substance of the drug.

Also, prolonged and uncontrolled use of the drug can lead to severe vaginal dysbiosis, which will only aggravate the course of candidiasis and complicate its treatment. Recall that Metronidazole will help against thrush only if, as a result of bacteriological seeding of pathological materials, cultures of fungi and pathogenic bacteria in the diagnostic titer are isolated from the vagina.

Price and where to buy?

Buying the drug is not difficult, as it is easy to find in almost any pharmacy chain. The price for one package with tablets (10 or 20 pieces) ranges from 50 to 150 rubles. Metronidazole intravaginal suppositories are somewhat more expensive, their cost starts at 200 rubles for 7 suppositories.

From this article you will learn: when Metronidazole is prescribed for thrush, indications for use, in which cases the drug is not suitable. Mechanism of action as Metronidazole is used. Possible Complications and contraindications, side effects.

Article publication date: 10/29/2017

Article last updated: 11/28/2018

Metronidazole is a drug that is active against pathogenic bacteria and unicellular protozoa (amoebae, Giardia, Trichomonas).

The drug does not have an antifungal effect, its appointment for thrush can be justified when the process proceeds against the background of:

vaginal dysbiosis (dysbacteriosis with a predominance of pathogenic bacteria);
sexually transmitted infections (trichomoniasis);
mixed infections (bacteria, protozoa, fungi).

In these cases, Metronidazole is prescribed in 89–92%, occasionally preferring other antibacterial agents to it. It quickly restores the normal microflora of the genital tract and normalizes local immunity, indirectly affecting the disappearance of pathogenic fungi (the main cause of thrush is weakened general or local immunity).

In the treatment of thrush, Metronidazole is not prescribed without any drug directed fungicidal action, since it is not effective against Candida albicans fungi (causative agents of candidiasis in 80% of cases) and can only temporarily eliminate the pronounced symptoms of the disease.

One of the representatives of antifungal agents is Fluconazole. The doctor may prescribe the drug in various dosages, depending on the characteristics and severity of the thrush.

The drug equally well helps both men and women due to the wide indications for use:

For the treatment of sexually transmitted protozooses, they turn to a dermatovenereologist.

With mixed bacterial and fungal infections of the genital tract in women - to a gynecologist, in men - to a urologist.

For diseases of the stomach and intestines - see a gastroenterologist.

When is metronidazole prescribed?

Metronidazole is a drug with a wide antibacterial and antiprotozoal action, it is prescribed for the treatment of:

mixed infection of the genital tract (caused by fungi, bacteria, Trichomonas) in women and men;
pseudomembranous enterocolitis (inflammation of the intestine against the background of antibiotic therapy);
inflammatory diseases of the vulva, vagina and uterus (except for the cervix) in women;
gastritis, gastric and duodenal ulcers, provoked by the bacterium Helicobacter pylori (in combination with the antibiotic amoxicillin);
protozoal intestinal and non-intestinal infections (amebiasis, balantidiasis, giardiasis, trichomoniasis, giardiasis);
ulcerative stomatitis;
bacterial infections of the pelvic organs (colpitis, endometritis, abscesses of the fallopian tubes and ovaries in women, acute inflammatory processes in the abdominal cavity);
bacterial processes of the central nervous system (meningitis, brain abscess);
bacterial pathologies of bones, joints, connective tissue, skin (endocarditis, pneumonia, pyogenic arthritis, trophic ulcers, etc.).

Metronidazole helps fight Trichomonas

For prevention:

inflammatory complications after major and minor surgical interventions.

Metronidazole increases the resistance of healthy tissues and increases the susceptibility cancer cells in radiotherapy of oncological tumors. With the complex treatment of thrush, it enhances the effect of antifungal antibiotics.

In what cases the drug is not suitable

The drug is ineffective in the treatment of bacterial infections that are insensitive to the active substance of the drug (for example, those caused by staphylococci and streptococci). Therefore, its appointment is made on the basis of sowing biological material (scraping, smear, secretions) from the lesion.

Mechanism of action

The active ingredient in Metronidazole is nitroimidazole metronidazole. The action is based on the activation of the substance due to the transport proteins of protozoa and bacteria. They attach and reduce it to a form that can inhibit the synthesis of nucleic acids ( constituent parts DNA). This causes the death of pathogenic microorganisms.

The remedy is 99% effective against trichomoniasis, 82–85% effective against mixed pathogenic microflora in combination with antifungal agents.

Metronidazole from thrush is prescribed as an auxiliary antibacterial and antiprotozoal agent when a secondary or sexual infection is attached.

How is Metronidazole used?

Forms of release of metronidazole

In the treatment of thrush in combination with a secondary bacterial infection, different dosage forms of Metronidazole are used in this way:

The gel is applied to the mucous membrane using a special applicator, 5 g twice a day (the course is 5 days) or a thin layer on the affected surfaces (skin), previously washed and dried (the full course of treatment lasts from 1 to 4 months).

Suppositories are inserted as deep as possible into the vagina once a day (treatment is continued for 10-12 days, repeating courses if necessary).

Tablets for the treatment of bacterial complications (including in combination with urogenital candidiasis) are taken twice a day (daily dose should not exceed 2 g). The duration of the course is adjusted by the attending physician, it usually lasts from 7 to 10 days. Other associated sexual infections (trichomoniasis) are treated with a total daily dose of 400 mg for a week.

Injections are intended for the treatment of bacterial complications (abscesses) or severe protozoal infections (intestinal amoebiasis, dysentery), when the appointment of other forms of the drug is ineffective. In these cases, the dosage and duration of the course is determined individually.

Metronidazole tablets are prescribed for the prevention of bacterial complications before (from 750 to 1500 mg per day, 3-4 days) or after surgery (1000 mg once).

Possible Complications

When using the solution at the injection site, thrombophlebitis (inflammation of nearby subcutaneous vessels) appears quite rarely (1–2%), which is accompanied by swelling, redness, and pain.

A long course of treatment with Metronidazole can also cause thrush. The action of the drug is not selective, it inhibits the growth and development of any bacterial flora. This causes suppression of local immunity and the development of a fungal infection (candidiasis).

When taking alcoholic beverages, medicines on ethanol and Metronidazole appear sharp headaches, nausea, abdominal cramps, vomiting.

The drug may cause a false positive Nelson-Meyer test for syphilis.

Oral candidiasis caused by taking antibacterial agents against a background of reduced immunity

Contraindications

Metronidazole is contraindicated for use in:

organic diseases of the central nervous system (epilepsy);
low levels of white blood cells (leukopenia) in the blood;
allergies to the constituent components of the product;
pregnancy (in the 1st trimester, with caution in another period);
breastfeeding;
liver diseases (insufficiency, cirrhosis).

The drug is not prescribed for children under one year old and carefully combined with indirect anticoagulants, this can cause clotting disorders.

Today, one of the most popular indirect anticoagulants is Warfarin. Metronidazole with indirect anticoagulants is combined carefully

Side effects

The use of Metronidazole can cause numerous side effects:

Central nervous system reacts with headaches, speech and coordination disorders, weakness, lethargy, irritability, the appearance of hallucinations, and insomnia.

Gastrointestinal tract - dryness, taste of metal in the mouth, vomiting, nausea, stool disorders, gastrointestinal colic, the appearance of stomatitis, glossitis.

The genitourinary system - the appearance of thrush and cystitis, a change in the quality (red-brown color) and quantity (increase) of urine.

An allergy to the drug manifests itself in the form of skin rashes and redness, nasal congestion, temperature changes, joint pain.

The drug is able to change the number of leukocytes in the blood formula (reduce) and ECG readings.

Owner and responsible for the site and content: Afinogenov Alexey.

Metronidazole is an antiprotozoal, antimicrobial agent that has a detrimental effect on harmful bacteria in the body. Assign for the treatment of bacterial infections of the genital organs, gastrointestinal tract, skin, respiratory organs.

The following agents are sensitive to the dosage form:

trichomonas;
lamblia;
gardnerella;
proteus, amoeba.

In gynecology, metronidozal is prescribed for endometriosis of various etiologies, pelvic abscesses, after abortion, septic condition after surgery. Good results are obtained in the treatment of thrush.

Does metronidazole help with candidiasis

Currently, there are many ways to cure the disease. Modern drugs very quickly and effectively relieve candidiasis in men and women. One such effective drug is Metronidazole for thrush. It is prescribed in the acute course of the disease and strictly in combination with other drugs.

Can I take just one metronidazole? The drug itself does not help with candidiasis, if other medicines are not taken.

Release form

Metronidazole is available in the form:

tablets;
creams for external use;
candles;
solution for injection.

metronidazole tablets

Such from the intestines enter the bloodstream, and are carried to all organs and systems. The active substance is found in all biological fluids: saliva, bile, cerebrospinal fluid. Also goes to bone tissue, breast milk. More than 81% is excreted through the kidneys, the rest with bile.

Metronidazole with thrush should be taken according to general scheme. Depending on how the disease proceeds, 1 tablet is prescribed 1-2 times a day. Take one hour before meals or 2-3 hours after meals, without chewing or crushing. The drug taken must be washed down with water or milk. The course of treatment is not more than 7 days.

The average dose is 250-500 mg twice a day. Dosage and time of admission depends on the severity of the disease and indications.

For children under 3 years of age, the drug is contraindicated.

Cream for external use

Gel or has White color, average consistency density. It is not absorbed from the surface of the skin. The action is local, it is used only for fungal infections. The gel has a high penetrating property. Therefore, its use is much more effective than taking pills. Even with the minimum dosage of the injected agent, the most positive effect is achieved. therapeutic effect. The occurrence of side effects is significantly reduced.

How to use vaginal gel for candidiasis

The procedure is carried out in the supine position or in any other position that is comfortable for the woman. The gel is injected into the vagina using a special applicator in the amount of 5 g. Therapeutic action starts at 7 o'clock. Do the procedure in the evening, once a day. For chronic use twice.

After that, do not take a shower or bath for 6 hours. The applicator is well washed and processed disinfectant. Do this every time after manipulation. The duration of treatment is not more than 10 days.

Metronidazole solution for candidiasis

A solution of metronidazole is slightly yellowish in color with a greenish tinge. It is used for severe thrush, which occurs with concomitant infections of the pelvic organs or genital organs. Enter intravenously bolus 500 ml for 20 minutes. The interval between the injected solutions is at least 7-8 hours. The duration of such treatment is prescribed by the doctor.

Homemade tampons with metronidazole for thrush

Metronidazole tampons are often used by gynecologists in the treatment of vaginal candidiasis. Assign for mild and acute form of the disease.

A roller up to 8 cm is made from sterile cotton wool, moistened in the finished solution. Wrap with a sterile bandage. The woman lies on her back, inserts the tampon not deep, so that later it can be removed without problems.

You can put tampons no more than 2 times a day. The course of treatment is prescribed for each patient individually.

Side effects and possible complications

No serious side effects are known. Some patients complain of nausea, dizziness, headache, increased activity, urinary incontinence, diarrhea, vomiting, anaphylaxis, blood changes, and poor sleep. With topical application of the drug, itching, irritation, redness is possible.

Contraindications for use

Metronidazole is contraindicated in:

organic lesions of the central nervous system;
epilepsy;
blood disease - leukopenia;
liver failure, if large doses are prescribed;
hypersensitivity to this drug;
first trimester of pregnancy, carefully used in the second and third trimesters, while breastfeeding;
kidney failure.

Does metronidazole destroy the liver?

The drug has low toxicity and rarely causes toxic effects.